Clinical trial · Interventional
Super-voltage PRF of Stellate Ganglion Versus Super-voltage PRF of T2 T3 Sympathetic Ganglia in Managing PMPS.
Super-voltage Pulsed Radiofrequency of Stellate Ganglion Versus Super-voltage Pulsed Radiofrequency of T2 T3 Sympathetic Ganglia in Managing Postmastectomy Pain Syndrome.
NCT07675096CI-TRIAL-00116333PMPS PRFnot yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to compare the effectiveness of super-voltage pulsed radiofrequency of stellate ganglion and super-voltage pulsed radiofrequency of T2-T3 sympathetic ganglia in the treatment of postmastectomy pain syndrome.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chronic Pain Following Surgical Procedure for Cancer | — | UNRESOLVED | — |
| Post Mastectomy Pain Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Group S : Stellate Ganglion supervoltage pulsed radiofrequency | Procedure | — | UNRESOLVED |
| Group T : T2-T3 chains supervoltage pulsed radiofrequency. | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Group S: Stellate Ganglion super-voltage pulsed radiofrequency
- description
- Super-voltage pulsed radiofrequency (PRF) of the stellate ganglion was performed under strict aseptic precautions with standard monitoring. Patients were positioned supine with a slight extension of the neck and head turned contralaterally. Ultrasound guidance using a high-frequency linear transducer was employed to identify the stellate ganglion region at the level of the C6 transverse process, anterior to the longus colli muscle and medial to the carotid sheath. A 22-gauge radiofrequency cannula (5-10 cm length, 5-mm active tip) was advanced using an in-plane technique until the needle tip was positioned adjacent to the sympathetic chain on the surface of the longus colli muscle. After negative aspiration, sensory (50 Hz) and motor (2 Hz) stimulation were performed to confirm appropriate needle placement and exclude somatic nerve involvement.
- interventionNames
- Procedure: Group S : Stellate Ganglion supervoltage pulsed radiofrequency
- type
- ACTIVE_COMPARATOR
- label
- Group T: T2-T3 chains supervoltage pulsed radiofrequency
- description
- Position the patient prone with bolsters to minimize lordosis and allow C- arm AP and oblique imaging. Under sterile conditions use fluoroscopy to identify T2 and T3 pedicles, ribs and transverse processes. A posterior paravertebral (transforaminal-style) approach is commonly used: advance a curved RFA cannula (20-22G, 10-15 cm with 5-10 mm active tip) under fluoroscopic AP and lateral guidance to the anterolateral aspect of the vertebral body or just anterior to the costotransverse junction at the T2 and T3 levels, the expected location of the thoracic sympathetic chain. Confirm needle position with small (0.5-1 mL) contrast injection to exclude intravascular or pleural spread. Perform sensory (50 Hz) and, if applicable, motor (2 Hz) stimulation to exclude intercostal motor/pleural/nerve root proximity.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * Female patients aged 18-60 years. * Patient of class II according to the American society of Anesthesiologists (ASA) physical status classification system. * History of unilateral mastectomy for breast cancer. * Persistent pain \>3 months postoperatively. * VAS score ≥4 despite pharmacological management. * Patients with neuropathic pain who has a score ≥4 by (DN4) questionnaire. * Patients on more than 1 antineuropathic drug. Exclusion Criteria: * Coagulopathy or anticoagulant therapy. * Local infection at injection site. * History of psychiatric illness or cognitive dysfunction. * Previous intervention in the same region (e.g., prior stellate ganglion block or thoracic radiofrequency ablation). * Allergy to local anesthetics or contrast agents.
References
Publications (0)
Data not yet available
No reference posted for this study.