Clinical trial · Interventional
Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention
NCT07662239CI-TRIAL-00123929AYA-ONErecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study will evaluate strategies to improve physical function and promote exercise and physical activity in adolescents and young adults (AYAs) with sarcoma. The study will assess the feasibility of a standardized triage system for referring AYAs with sarcoma to appropriate exercise and rehabilitation services, and will also examine changes in physical function and health-related quality of life before and after a 12-week personalized exercise program.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Sarcoma | Bone Sarcoma | ONTOLOGY_EXACT | 0.98 |
| Sarcoma | Sarcoma | ONTOLOGY_EXACT | 0.98 |
| Soft Tissue Sarcoma (STS) | Soft Tissue Sarcoma | ONTOLOGY_EXACT | 0.85 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise Triage and Personalized Exercise Program | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Exercise Triage and Personalized Exercise Program
- description
- All participants receive this intervention.
- interventionNames
- Behavioral: Exercise Triage and Personalized Exercise Program
Primary outcomes (2)
- measure
- Triage Tool Completion Rate
- timeFrame
- 2 weeks
- description
- Triage tool completion rate is defined as the proportion of consented participants who fully completed the Exercise in Cancer Evaluation and Decision Support (EXCEEDS) tool.
- measure
- Referral Completion Rate
- timeFrame
- Within 2 months of EXCEEDS completion
- description
- Referral completion rate is defined as the rate of participants who completed the EXCEEDS tool and subsequently completed an initial visit with an occupational therapist (OT), physical therapist (PT), trainer, or health coach.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 39 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosed with a bone or soft tissue sarcoma * Age 15-39 at time of diagnosis * Age 15 and older at time of enrollment * Age 15-17 at time of enrollment, with assent from participant and consent from parent/legal guardian * Established patient of the DFCI Sarcoma Center or Jimmy Fund * Able to read and understand English (to complete required questionnaires and participate in training/coaching) * Individuals who are not yet adults (teenagers) if they assent and their parents/legal guardians' consent to participation. Exclusion Criteria: * Unstable cardiovascular disease in the last 6 months * Psychiatric disorders or conditions that would preclude participation in the study intervention (e.g. untreated major depression or psychosis, untreated substance use disorder, severe personality disorder) * Pregnant * Currently participating in physical or occupational therapy * Presence of medical conditions or medications that would prohibit participation in an exercise program * Meeting exercise guidelines of 150 minutes of moderate intensity/75 minutes of vigorous intensity physical activity per week plus consistent strength training (at least once per week) over the past 3 months. Assessed via Godin Leisure Time Questionnaire by study staff. * Adults unable to consent
References
Publications (0)
Data not yet available
No reference posted for this study.