Clinical trial · Interventional
RISS Versus SPSIP Block in Modified Radical Mastectomy
Comparison of Rhomboid Intercostal-Subserratus Plane Block and Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia and Dermatomal Spread After Modified Radical Mastectomy: A Randomized Double-Blind Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This prospective randomized double-blind controlled trial aims to compare the postoperative analgesic efficacy and dermatomal spread of rhomboid intercostal-subserratus plane (RISS) block and serratus posterior superior intercostal plane (SPSIP) block in patients undergoing modified radical mastectomy. Postoperative pain scores, opioid consumption, rescue analgesic requirements, block-related complications, and quality of recovery outcomes will be evaluated.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Postoperative Pain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Rhomboid Intercostal-Subserratus Plane Block | Procedure | — | UNRESOLVED |
| Serratus Posterior Superior Intercostal Plane Block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- RISS Block
- description
- Patients will receive an ultrasound-guided rhomboid intercostal-subserratus plane (RISS) block before modified radical mastectomy for postoperative analgesia.
- interventionNames
- Procedure: Rhomboid Intercostal-Subserratus Plane Block
- type
- EXPERIMENTAL
- label
- SPSIP Block
- description
- Patients will receive an ultrasound-guided serratus posterior superior intercostal plane (SPSIP) block before modified radical mastectomy for postoperative analgesia.
- interventionNames
- Procedure: Serratus Posterior Superior Intercostal Plane Block
Primary outcomes (1)
- measure
- Total Postoperative Opioid Consumption
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Female patients aged 18-75 years * ASA physical status I-III * Scheduled for elective unilateral modified radical mastectomy with axillary dissection under general anesthesia * Provision of written informed consent Exclusion Criteria: * Anticoagulant therapy * Bleeding diathesis * Known allergy to local anesthetics or opioids * Infection at the block application site or previous surgery in the block area * Cognitive impairment preventing NRS assessment * Pregnancy or lactation * Chronic opioid use * Severe hepatic or renal failure * Refusal to participate in the study * Technical inability to perform the block or failed block
References
Publications (0)
Data not yet available