Clinical trial · Observational
Mean Platelet Volume (MPV) as an Early Predictor of Mortality in Intensive Care Patients With Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to investigate whether Mean Platelet Volume (MPV) and other blood count parameters measured at admission can predict mortality in cancer patients admitted to the intensive care unit (ICU). Patients with cancer are highly vulnerable to complications and organ failure, making early risk assessment vital for improving treatment strategies. Researchers will retrospectively review the medical charts and electronic health records of adult patients who stayed in the anesthesia ICU for longer than 24 hours between 2020 and 2025. No new laboratory tests, interventions, or patient contact will occur. The collected data will be analyzed to determine the relationship between initial MPV levels and patient survival outcomes.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Critical Illness | — | UNRESOLVED | — |
| Mortality | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Oncological ICU Patients
- description
- Adult patients (aged 18 and older) with a confirmed cancer diagnosis who were admitted to the anesthesia intensive care unit for longer than 24 hours between the years 2020 and 2025
Primary outcomes (1)
- measure
- Intensive Care Unit (ICU) Mortality
- timeFrame
- From the date of ICU admission up to ICU discharge, assessed up to 30 days.
- description
- The percentage of oncological patients who died during their stay in the anesthesia intensive care unit. This will be calculated based on the electronic health records and patient files.
Secondary outcomes (1)
- measure
- Hospital Mortality
- timeFrame
- From the date of hospital admission up to hospital discharge, assessed up to 60 days.
- description
- The percentage of oncological patients who died during their overall hospital stay (including post-ICU ward follow-up).
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients aged 18 years and older. * Patients with a pathologically or clinically confirmed diagnosis of cancer (solid or hematological malignancies). * Patients who were admitted to the Anesthesia Intensive Care Unit (ICU) between 2020 and 2025. * Patients with an ICU length of stay longer than 24 hours. * Patients with complete medical records, including baseline complete blood count (CBC) and Mean Platelet Volume (MPV) measured at the time of ICU admission. Exclusion Criteria: * Patients under the age of 18. * Patients who stayed in the intensive care unit for less than 24 hours. * Patients with missing or incomplete medical charts, laboratory data, or survival status records. * Patients who were readmitted to the ICU during the same hospital stay (only the first admission will be evaluated). * Patients who received massive blood or platelet transfusions immediately prior to the baseline laboratory measurement, which could artificially alter platelet parameters.
References
Publications (0)
Data not yet available