Clinical trial · Interventional
Incidental Thyroid Cancer in Cases With Inflammatory Thyroid Lesion
Incidental Thyroid Cancer in Patients With Inflammatory Thyroid Lesions: A Cohort Study From a Tertiary Care Center
NCT07652450CI-TRIAL-00121457Thyroid cancercompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aim to assess for the incidence of thyroid cancer in patients with autoimmune thyroiditis (Inflammatory thyroid Lesions)
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Follicular Thyroid Cancer | Thyroid Gland Follicular Carcinoma | ALIAS | 0.90 |
| Hashimoto's Thyroiditis | — | UNRESOLVED | — |
| Hashimoto Disease | — | UNRESOLVED | — |
| Papillary Thyroid Cancer | Thyroid Gland Papillary Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| total thyroidectomy | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Inflammatory thyroid lesions
- description
- The presence of thyroiditis was determined considering histological diagnosis taken post-surgery, and we considered the correlation between any presence of thyroiditis and all Differentiated thyroid cancer, taken from the histopathological examination after pathologic analysis.
- interventionNames
- Other: total thyroidectomy
Primary outcomes (1)
- measure
- • Incidence of incidental differentiated thyroid cancer with autoimmune thyroiditis
- timeFrame
- At time of surgery (postoperative histopathology)
- description
- Title: Incidence of incidental differentiated thyroid cancer Unit of measure: % of patients (proportion) Metric/method: Histopathological examination of surgical specimen
Secondary outcomes (8)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: 1. All types of autoimmune thyroiditis, including: * Graves' disease * Toxic multinodular goiter (TMNG) * Toxic nodule (TN) * Hashimoto thyroiditis * Unspecified toxic nodular goiter 2. Age between 18 and 60 years 3. Underwent thyroid surgical operation (lobectomy or total thyroidectomy) Exclusion Criteria: 1. Patients with known differentiated thyroid cancer before surgery 2. Recurrent thyroid disease (previous thyroid surgery) 3. Patients unfit for operation (American Society of Anesthesiologists grade IV or V) 4. Incomplete histopathological data 5. Patients with medullary thyroid carcinoma or anaplastic thyroid cancer
References
Publications (0)
Data not yet available
No reference posted for this study.