Clinical trial · Observational
Human Observatory Study
The Human Observatory: A Prospective Individual and Population-Level Study of Aging, Health, and Longevity
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 9, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260909-000002
Summary
Brief summary (as posted)
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level. Individual multi-system clinical data from enrolled participants are linked to a continuously-ingested ecological data infrastructure spanning environmental exposures, social determinants, genealogical and family history records, mortality data, and population health databases at geographic resolutions from home address to global scale and beyond. The resulting model generates individual screening recommendations informed by population-level causal estimates, and population-level causal forecasts anchored by present-timepoint individual clinical biology. This linkage creates a feedback architecture designed to improve both simultaneously.
Conditions
Conditions (19)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Activities of Daily Living | — | UNRESOLVED | — |
| Aging | — | UNRESOLVED | — |
| All-cause Mortality | — | UNRESOLVED | — |
| Cardiovascular Diseases | — | UNRESOLVED | — |
| Cognitive Dysfunction | — | UNRESOLVED | — |
| Dementia | — | UNRESOLVED | — |
| Environmental Exposure | — | UNRESOLVED | — |
| Frailty | — | UNRESOLVED | — |
| Health Equity | — | UNRESOLVED | — |
| Health Related Quality of Life |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Multi-Domain Ecological and Clinical Data Linkage | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Life Expectancy Estimates by Geography
- timeFrame
- From enrollment until death, assessed periodically, up to 100 years
- description
- Continuously-updated life expectancy point estimates with credible intervals generated at individual, neighborhood, ZIP code, county, state, national, global, and beyond-earth scales using individual clinical data linked to population mortality records, environmental context, and ecological data.
- measure
- Geographic Disease Cluster and Outbreak Detection
- timeFrame
- From enrollment until death, assessed periodically, up to 100 years
- description
- Statistically anomalous concentrations of incident disease, mortality spikes, or shared symptom patterns at neighborhood and community resolution.
Secondary outcomes (8)
- measure
- Individual Screening Recommendation Accuracy
- timeFrame
- From enrollment until death, assessed periodically, up to 100 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Enrolled in the 100-Year Human Aging Study at any fixed or mobile clinical site; OR completion of online health screener with provision of geographic anchor data and consent. Exclusion Criteria: * Age under 18 years (current protocol; pediatric amendment planned).
References
Publications (0)
Data not yet available