Clinical trial · Interventional
Safety of Opportunistic Salpingectomy During Elective Laparoscopic Cholecystectomy.
Safety of Opportunistic Salpingectomy During Elective Laparoscopic Cholecystectomy: A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The knowledge, coupled with epidemiological studies demonstrating lower ovarian cancer rates in women with a history of tubal sterilization has led to recommendations for opportunistic salpingectomy at the time of benign gynecological surgery. However, this recommendation was not explored in the setting of non-gynecological surgeries, of most if the surgery performed not in pelvis. This study aims to evaluate the safety of performing opportunistic salpingectomy at the time of elective laparoscopic cholecystectomy in women aged 45 years or older. Of note, the only available prospective study from Austria evaluated feasibility of combined operation. By assessing complication rates and other perioperative outcomes, the study seeks to determine if this combined approach is a safe for opportunistic ovarian cancer prevention. Ultimately, this research may inform surgical practice and potentially reduce the incidence of ovarian cancer in this population.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cholecystolithiasis | — | UNRESOLVED | — |
| Ovarian Cancer | Malignant Ovarian Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cholecystectomy | Procedure | — | UNRESOLVED |
| Opportunistic salpingectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Experimental group
- description
- Opportunistic salpingectomy during surgery.
- interventionNames
- Procedure: Opportunistic salpingectomy
- Procedure: Cholecystectomy
- type
- ACTIVE_COMPARATOR
- label
- Control group
- description
- Elective cholecystectomy
- interventionNames
- Procedure: Cholecystectomy
Primary outcomes (1)
- measure
- Postoperative complications assesed with Comprehensive complication index.
- timeFrame
- within 6 weeks after surgery
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Women aged 45 years or older. * No known history of ovarian or fallopian tube cancer. * Completed family planning. * Scheduled to undergo elective laparoscopic cholecystectomy for benign gallbladder disease. * Able to provide informed consent. * Willing to comply with study procedures and follow-up assessments. Exclusion Criteria: * Previous abdominal Surgery or any inflammatory bowel disease. * Current pregnancy or breastfeeding (verbally asked). * Contraindications to laparoscopic surgery (e.g., severe cardiopulmonary disease, extensive prior abdominal surgery). * Any medical condition that, in the opinion of the investigator, would preclude safe participation in the study or interfere with follow-up. * Participation in another clinical trial that may confound the results of this study.
References
Publications (0)
Data not yet available