Clinical trial · Interventional
Effect of Progressive Muscle Relaxation and Diaphragmatic Breathing on Sleep Disturbances in Chemotherapy Patients
Effect of Progressive Muscle Relaxation and Diaphragmatic Breathing Techniques on Sleep Disturbances in Cancer Patients Undergoing Chemotherapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized controlled trial aims to investigate the effect of combined Progressive Muscle Relaxation (PMR) and Diaphragmatic Breathing (DB) techniques on sleep disturbances among patients receiving chemotherapy. Sleep disturbances are common among cancer patients undergoing chemotherapy and may negatively affect physical recovery, emotional well-being, and quality of life. Participants will be randomly assigned to either an intervention group receiving PMR and DB training in addition to routine care or a control group receiving routine care alone. Sleep outcomes will be assessed using the Pittsburgh Sleep Quality Index (PSQI), sleep diary records, and wearable sleep monitoring devices. The study seeks to determine whether the combined intervention can improve sleep quality and reduce sleep-related problems in chemotherapy patients.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Sleep Disorders | — | UNRESOLVED | — |
| Sleep Disturbance | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Progressive Muscle Relaxation and Diaphragmatic Breathing | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- PMR and Diaphragmatic Breathing Group
- description
- Participants will receive Progressive Muscle Relaxation and Diaphragmatic Breathing exercises in addition to traditional medical treatment during the study period.
- interventionNames
- Behavioral: Progressive Muscle Relaxation and Diaphragmatic Breathing
- type
- NO_INTERVENTION
- label
- Traditional treatment group
- description
- Participants will receive traditional medical treatment only without the relaxation and breathing intervention program.
Primary outcomes (1)
- measure
- Sleep Quality
- timeFrame
- Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * • Aged between 40-60 years * Both male and female patients * Currently receiving at least the second cycle of chemotherapy * Receiving chemotherapy protocols (Zhou et al., 2022) * PSQI score \> 5 at baseline indicating poor sleep quality * BMI between 18.5 and 30 * Able to provide informed consent Exclusion Criteria: * Diagnosed with sleep disorders unrelated to chemotherapy (e.g., obstructive sleep apnea) * Current use of sleep medications or anti-anxiety drugs * Diagnosed with major psychiatric conditions * Cognitive impairment limiting understanding of instructions * Severe cardiopulmonary comorbidities * Recent participation in relaxation-based clinical trials
References
Publications (4)
- BACKGROUNDMustian, K. M., et al. (2017). Treatment of sleep disturbance in cancer patients. Journal of Clinical Oncology.
- BACKGROUNDIrwin MR. Why sleep is important for health: a psychoneuroimmunology perspective. Annu Rev Psychol. 2015 Jan 3;66:143-72. doi: 10.1146/annurev-psych-010213-115205. Epub 2014 Jul 21. PMID 25061767
- BACKGROUNDJerath R, Edry JW, Barnes VA, Jerath V. Physiology of long pranayamic breathing: neural respiratory elements may provide a mechanism that explains how slow deep breathing shifts the autonomic nervous system. Med Hypotheses. 2006;67(3):566-71. doi: 10.1016/j.mehy.2006.02.042. Epub 2006 Apr 18. PMID 16624497
- BACKGROUNDJacobson, E. (1938). Progressive Relaxation. University of Chicago Press.