Clinical trial · Observational
Validation of the Association Between the Abundance of Three Bacterial Genera in Stool Samples and the Risk of Gallbladder Cancer in South American Patients With Gallstones
NCT07635745CI-TRIAL-00114119completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In our previous work, we found three types of bacteria in stool samples from South American patients with gallstones linked to a higher risk of gallbladder cancer. The aim of the present study is to confirm these associations using a separate set of South American stool samples.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gallbladder Malignant Neoplasm | Malignant Gallbladder Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- South American patients with gallbladder cancer
- label
- South American patients with gallstones, with no evidence of gallbladder cancer upon pathological ex
Primary outcomes (1)
- measure
- Validation of the Association Between Gallbladder Cancer Risk in South American Patients With Gallstones and the Centered Log-Ratio-Transformed Abundance of Three Stool Bacterial Genera Determined by Shotgun Metagenomic Sequencing
- timeFrame
- Baseline
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with gallstones and cancer-free OR - Patients with gallbladder cancer Exclusion Criteria: * Antibiotics use
References
Publications (0)
Data not yet available
No reference posted for this study.