Clinical trial · Interventional
Home-based Vision Rehabilitation Guided by Brain Imaging
Behavioral Rehabilitation Through Image-Guided Home-based Training
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260915-000001
Summary
Brief summary (as posted)
The BRIGHT (Behavioral Rehabilitation Through Image-Guided Home-based Training) study aims to evaluate the effectiveness of image-guided, home-based perceptual training at improving visual performance in individuals with visual field loss. Using a prospective, crossover design, BRIGHT combines visual behavioral testing, neuroimaging, and a home-based intervention. It aims to 1) identify neural pathways that support training-induced visual plasticity; and 2) compare the efficacy of different types of visual training delivered in a home-based setting.
Conditions
Conditions (9)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Tumor | Brain Neoplasm | ALIAS | 0.90 |
| Cortical Blindness | — | UNRESOLVED | — |
| Hemianopia Homonymous | — | UNRESOLVED | — |
| Quadrantanopia | — | UNRESOLVED | — |
| Stroke | — | UNRESOLVED | — |
| Traumatic Brain Injury | — | UNRESOLVED | — |
| Visual Field Defect | — | UNRESOLVED | — |
| Visual Field Defect, Peripheral | — | UNRESOLVED | — |
| Visual Field Loss | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| High-level perceptual learning-based training | Behavioral | — | UNRESOLVED |
| Low-level perceptual learning-based training | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Perceptual learning-based training using high-level visual stimuli
- description
- A 3 week at-home online perceptual learning-based training using high-level visual stimuli.
- interventionNames
- Behavioral: High-level perceptual learning-based training
- type
- ACTIVE_COMPARATOR
- label
- Perceptual learning-based training using low-level visual stimuli
- description
- A 3 week at-home online perceptual learning-based training using low-level visual stimuli.
- interventionNames
- Behavioral: Low-level perceptual learning-based training
Primary outcomes (2)
- measure
- Change in high-level perceptual discrimination performance
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. At least 18 years of age. 2. Capable of providing informed consent and complying with study procedures. 3. Unilateral or bilateral focal brain damage causing visual field loss. 4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year. 5. Eligible for MRI based on standard safety screening. Exclusion Criteria: 1. Severe neurological or psychiatric conditions unrelated to the focal lesion that may interfere with study participation or data interpretation. 2. Current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5. 3. Ocular disease or disorder.
References
Publications (0)
Data not yet available