Clinical trial · Interventional
Clinical Study of a New Treatment Model for Elderly Lung Cancer Patients
A Multicenter Clinical Study on a New Treatment Model Combining New Surgical Techniques, Perioperative Comprehensive Treatment, and Postoperative Rehabilitation for Elderly Patients With Lung Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This multicenter prospective clinical study focuses on elderly patients with lung cancer. The investigators will build a standardized clinical registry database, develop perioperative risk stratification and surgical early-warning models, optimize individualized surgical regimens, construct multidisciplinary perioperative comprehensive therapy, integrated Chinese-Western medicine full-cycle management and personalized postoperative rehabilitation systems, so as to form a whole-process optimized treatment model for elderly lung cancer.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aged | — | UNRESOLVED | — |
| Lung Neoplasm | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Perioperative Care | — | UNRESOLVED | — |
| Postoperative Rehabilitation | — | UNRESOLVED | — |
| Thoracic Surgical Procedures | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Pulmonary Lobectomy plus Mediastinal Lymph Node Sampling | Procedure | — | UNRESOLVED |
| Pulmonary Segmentectomy plus Mediastinal Lymph Node Sampling | Procedure | — | UNRESOLVED |
| Pulmonary Wedge Resection plus Mediastinal Lymph Node Sampling | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Lobectomy Group
- description
- Patients receive standard lobectomy plus mediastinal lymph node sampling for early-stage non-small cell lung cancer, for elderly patients ≥65 years with T1N0M0 tumor. Postoperative standard perioperative management and regular follow-up are conducted.
- interventionNames
- Procedure: Pulmonary Lobectomy plus Mediastinal Lymph Node Sampling
- type
- EXPERIMENTAL
- label
- Segmentectomy Group
- description
- Patients receive anatomic segmentectomy plus mediastinal lymph node sampling. All enrolled elderly patients are stratified by tumor size and preoperative geriatric risk score before randomization, followed by unified postoperative monitoring and adaptive perioperative treatment based on MRD and biomarker results.
- interventionNames
- Procedure: Pulmonary Segmentectomy plus Mediastinal Lymph Node Sampling
- type
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: 1. Aged ≥65 years old 2. Pathologically confirmed non-small cell lung cancer with clinical stage eligible for curative surgical resection 3. Complete preoperative geriatric comprehensive assessment data available 4. Capable of finishing planned surgery and long-term follow-up 5. Voluntarily sign informed consent form Exclusion Criteria: 1. History of other malignant tumors within recent 5 years 2. Severe organic dysfunction of heart, liver, renal or respiratory system that cannot tolerate thoracic surgery 3. Preoperative confirmed distant metastasis preventing radical resection 4. Uncontrolled active severe infection or obvious coagulation disorders 5. Severe psychiatric disorder or cognitive dysfunction failing to cooperate with treatment and follow-up 6. Refuse random grouping and postoperative regular monitoring
References
Publications (0)
Data not yet available