Clinical trial · Observational
Non-Invasive Malignancy Classifiers Using Blood-Biomarkers for Lung Nodule Evaluation
NIMBLE | Non-Invasive Malignancy Classifiers Using Blood-Biomarkers for Lung Nodule Evaluation
NCT07623473CI-TRIAL-00113447NIMBLErecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of the NIMBLE study is to evaluate blood-based biomarkers for lung cancer risk prediction in patients referred with a lung nodule. Each blood biomarker will be evaluated for descriminating malignant from benign lung nodules alone and in combination with other blood biomarkers, patient characteristics and radiological features.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer (Diagnosis) | Malignant Lung Neoplasm | CURATED_EXACT | 0.85 |
| Nodule, Solitary Pulmonary | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood tests | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients referred for work-up suspected of lung cancer
- description
- Patients are enrolled when these are referred to the Pulmonology Department suspected of lung cancer.
- interventionNames
- Diagnostic Test: Blood tests
Primary outcomes (1)
- measure
- Lung cancer diagnosis during work-up
- timeFrame
- At least two years of followup
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients with a newly detected IPN suspected of lung cancer referred to the infiltrate unit * Having signed informed consent Exclusion Criteria: * Active cancer, excluding non-melanoma skin cancer * Comorbidities that exclude the patient from clinical follow-up and final diagnosis
References
Publications (0)
Data not yet available
No reference posted for this study.