Clinical trial · Observational
Multiparametric MRI for Bladder Cancer: Validation of VI-RADS for the Detection of Muscle Invasive Bladder Cancer
NCT07578233CI-TRIAL-00111075completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research aimed to determine how accurately multiparametric magnetic resonance imaging (MRI), when interpreted using the VI-RADS scoring system, can distinguish between invasive and non-invasive bladder cancer.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Magnetic Resonance Imaging | — | UNRESOLVED | — |
| Multiparametric | — | UNRESOLVED | — |
| Muscle Invasive Bladder Cancer | — | UNRESOLVED | — |
| Validation | — | UNRESOLVED | — |
| Vesical Imaging Reporting and Data System (VI-RADS) | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Magnetic resonance imaging | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Study group
- description
- Patients with bladder masses diagnosed through ultrasound, computed tomography, or magnetic resonance imaging, who were scheduled for cystoscopy
- interventionNames
- Other: Magnetic resonance imaging
Primary outcomes (1)
- measure
- Sensitivity of VI-RADS score for invasion through the bladder wall
- timeFrame
- 3 months after the procedure
- description
- Sensitivity of VI-RADS score for invasion through the bladder wall was recorded. At the end VI-RADS scoring was calculated using all categories, to know the probability of muscle invasion as follows: VI-RADS 1 (very low probability of muscle invasion ): SC, CE, and DW category 1; VI-RADS 2 (low probability of muscle invasion): SC, CE, and DW category 2; both CE and DW category 2 with SC category 3; VI-RADS 3 (muscle invasion is equivocal): SC, CE, and DW category 3; SC category 3 and CE or DW category 3, with the remaining sequence in category 2; (Category 3 should be applied when category 2 findings are absent in their respective sequences but there is no apparent disruption of the typical SI in the muscularis propria, there may be Misclassifications in the VI-RADS 2-3 group).
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Both sexes. * Patients with bladder masses diagnosed through ultrasound, computed tomography, or magnetic resonance imaging (MRI), who were scheduled for cystoscopy. Exclusion Criteria: * Contraindications to MRI (such as metallic prostheses or pacemakers). * Contraindications to Transurethral Resection (like unfitness for anesthesia or urethral strictures). * Elevated serum creatinine levels (precluding IV contrast-enhanced imaging).
References
Publications (0)
Data not yet available
No reference posted for this study.