Clinical trial · Observational
Thyroidectomy-specific Enhanced Recovery After Surgery (ERAS) Protocol
A Comprehensive Enhanced Recovery After Surgery (ERAS) Protocol for Thyroidectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Thyroidectomy is generally considered a low-to-moderate risk operation; however, postoperative pain, nausea/vomiting, and prolonged hospital stays remain common issues. Enhanced Recovery After Surgery (ERAS) pathways aim to optimize perioperative care and accelerate recovery. This study evaluates the effectiveness and safety of a standardized ERAS pathway in patients undergoing elective thyroidectomy. The prospective ERAS cohort is compared with a historical control group receiving conventional care to assess the impact on the length of hospital stay, postoperative pain, opioid consumption, and complication rates.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Goiter | — | UNRESOLVED | — |
| Thyroid Diseases | — | UNRESOLVED | — |
| Thyroid Neoplasms | Thyroid Gland Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional perioperative care | Procedure | — | UNRESOLVED |
| Enhanced Recovery After Surgery protocol | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- ERAS group
- description
- A prospective cohort undergoing elective thyroidectomy under an ERAS protocol.
- interventionNames
- Procedure: Enhanced Recovery After Surgery protocol
- label
- Control group
- description
- A historical control cohort undergoing thyroidectomy under conventional care during the 12 months preceding ERAS implementation
- interventionNames
- Procedure: Conventional perioperative care
Primary outcomes (1)
- measure
- Length of hospital stay
- timeFrame
- Up to 30 days post-surgery
- description
- Hours from surgery end to discharge
Secondary outcomes (5)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged 18-75 years * ASA physical status I-III. * Scheduled for elective thyroidectomy for benign or malignant disease. Exclusion Criteria: * Re-operative thyroid surgery * Concomitant neck dissection * Inability to comply with the ERAS pathway
References
Publications (5)
- BACKGROUNDAlthans AR, Holder-Murray J, Tessler RA. The Future of Enhanced Recovery After Surgery-Precision vs Protocol. JAMA Netw Open. 2024 Jun 3;7(6):e2418968. doi: 10.1001/jamanetworkopen.2024.18968. No abstract available. PMID 38888927
- BACKGROUNDSauro KM, Smith C, Ibadin S, Thomas A, Ganshorn H, Bakunda L, Bajgain B, Bisch SP, Nelson G. Enhanced Recovery After Surgery Guidelines and Hospital Length of Stay, Readmission, Complications, and Mortality: A Meta-Analysis of Randomized Clinical Trials. JAMA Netw Open. 2024 Jun 3;7(6):e2417310. doi: 10.1001/jamanetworkopen.2024.17310. PMID 38888922
- BACKGROUNDSimpson JC, Bao X, Agarwala A. Pain Management in Enhanced Recovery after Surgery (ERAS) Protocols. Clin Colon Rectal Surg. 2019 Mar;32(2):121-128. doi: 10.1055/s-0038-1676477. Epub 2019 Feb 28. PMID 30833861
- BACKGROUNDMachado N, Mortlock R, Maduka R, Souza Cunha AE, Dyer E, Long A, Canner JK, Tanella A, Gibson C, Hyman J, Ogilvie J. Early observations with an ERAS pathway for thyroid and parathyroid surgery: Moving the goalposts forward. Surgery. 2024 Jan;175(1):114-120. doi: 10.1016/j.surg.2023.06.052. Epub 2023 Nov 15. PMID 37973430
- BACKGROUNDLee DJ, Chin CJ, Hong CJ, Perera S, Witterick IJ. Outpatient versus inpatient thyroidectomy: A systematic review and meta-analysis. Head Neck. 2018 Jan;40(1):192-202. doi: 10.1002/hed.24934. Epub 2017 Nov 9. PMID 29120517