Clinical trial · Interventional
Dressing Methods in Inoperable Malignant Wounds
Comparison of PHMB-containing Dressings and Paraffin-based Tulle Dressings in the Management of Inoperable Malignant Wounds in Oncology Patients: A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized controlled study aimed to evaluate symptom burden and quality of life in oncology patients with inoperable malignant wounds. Patients were assigned to receive either polyhexamethylene biguanide (PHMB)-containing dressings or paraffin-based tulle dressings. Symptom severity and quality of life were assessed over a three-month follow-up period using standardized measures, including the Edmonton Symptom Assessment Scale (ESAS). The study primarily focuses on palliative outcomes rather than wound healing.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Inoperable Malignant Wounds | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Paraffin tulle dressing | Other | — | UNRESOLVED |
| PHMB-containing dressing | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- PHMB Group
- description
- Participants received PHMB-containing dressings.
- interventionNames
- Other: PHMB-containing dressing
- type
- ACTIVE_COMPARATOR
- label
- Paraffin Tulle Group
- description
- Participants received paraffin-based tulle dressings containing chlorhexidine.
- interventionNames
- Other: Paraffin tulle dressing
Primary outcomes (1)
- measure
- Change in symptom burden measured by the Edmonton Symptom Assessment Scale (ESAS)
- timeFrame
- Baseline to 3 months
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients aged 18 years and older * Diagnosed with cancer and having inoperable malignant wounds * Admitted to the wound care clinic * Able to provide informed consent Exclusion Criteria: * Patients with acute wounds * Patients with incomplete follow-up * Patients with conditions preventing adherence to the study protocol
References
Publications (0)
Data not yet available