Clinical trial · Interventional
Enhanced COPD Management in Suspected Lung Cancer Patients
Enhanced COPD Management in Suspected Lung Cancer Patients - Improving Outcomes Through Timely Intervention
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Identifying and treating COPD in patients undergoing lung cancer evaluation is crucial. Early intervention could lead to better management of both diseases, improving health status, reducing healthcare costs, and potentially increasing survival rates. This study aims to assess the impact of early diagnosis and optimal treatment of COPD on clinical outcomes in patients under evaluation for lung cancer. The study will combine information through an open-label RCT at the Lung Cancer Investigation Unit at Lillebaelt Hospital Vejle. The findings could inform clinical practice by emphasizing the importance of integrated care approaches for patients with coexisting COPD and lung cancer, ultimately leading to better health outcomes.
Conditions
Conditions (9)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Airflow Obstruction, Chronic | — | UNRESOLVED | — |
| COPD | — | UNRESOLVED | — |
| COPD (Chronic Obstructive Pulmonary Disease) | — | UNRESOLVED | — |
| Lung Cancer (Diagnosis) | Malignant Lung Neoplasm | CURATED_EXACT | 0.85 |
| Lung Carcinoma | Lung Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Lung Neoplasm Malignant | — | UNRESOLVED | — |
| Pulmonary Cancers | — | UNRESOLVED | — |
| Pulmonary Carcinoma | — | UNRESOLVED | — |
| Pulmonary Neoplasms | — | UNRESOLVED |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Tailored COPD consultations | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Usual care
- description
- Lung cancer investigation only
- type
- EXPERIMENTAL
- label
- Tailored COPD consultation
- description
- Tailored COPD consultations will include assessment and treatment according to GOLD guidelines, including: Pharmacological management Smoking cessation support Referral to pulmonary rehabilitation as appropriate Referral for nutritional assessment and optimization when appropriate Referral to cardiovascular evaluation when appropriate Referral to sleep apnea evaluation when appropriate
- interventionNames
- Other: Tailored COPD consultations
Primary outcomes (1)
- measure
- CAT score
- timeFrame
- Baseline, after 3 months and after 6 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Undergoing diagnostic evaluation for suspected lung cancer * Spirometry showing obstructive airflow limitation (FEV₁/FVC \< 75 % or FEV₁ \< 80 %, and no reversibility) at the first outpatient visit at the lung cancer evaluation Exclusion Criteria: * Presence of significant comorbidities that may interfere with diagnostic procedures or spirometry * Pregnant or breastfeeding women
References
Publications (30)
- BACKGROUNDHuang CY, Hsieh MS, Hsieh PC, Wu YK, Yang MC, Huang SY, Tzeng IS, Lan CC. Pulmonary rehabilitation improves exercise capacity, health-related quality of life, and cardiopulmonary function in patients with non-small cell lung cancer. BMC Cancer. 2024 Feb 15;24(1):211. doi: 10.1186/s12885-024-11977-5. PMID 38360680
- BACKGROUNDVagvolgyi A, Rozgonyi Z, Kerti M, Vadasz P, Varga J. Effectiveness of perioperative pulmonary rehabilitation in thoracic surgery. J Thorac Dis. 2017 Jun;9(6):1584-1591. doi: 10.21037/jtd.2017.05.49. PMID 28740672
- BACKGROUNDShin S, Kong S, Kang D, Lee G, Cho JH, Shim YM, Cho J, Kim HK, Park HY. Longitudinal changes in pulmonary function and patient-reported outcomes after lung cancer surgery. Respir Res. 2022 Aug 30;23(1):224. doi: 10.1186/s12931-022-02149-9. PMID 36042472
- BACKGROUNDIllini O, Valipour A, Gattinger D, Petrovic M, Fabikan H, Hochmair MJ, Zwick RH. Effectiveness of Outpatient Pulmonary Rehabilitation in Patients with Surgically Resected Lung Cancer: A Retrospective Real-World Analysis. Cancers (Basel). 2022 Jul 18;14(14):3479. doi: 10.3390/cancers14143479. PMID 35884540
- BACKGROUNDHuang CY, Hsieh MS, Wu YK, Hsieh PC, Yang MC, Tzeng IS, Lan CC. Chronic obstructive pulmonary disease assessment test for the measurement of deterioration and recovery of health status of patients undergoing lung surgery. Thorac Cancer. 2022 Feb;13(4):613-623. doi: 10.1111/1759-7714.14306. Epub 2022 Jan 6. PMID 34989126
- BACKGROUNDDeng D, Peng D, Song Q, Lin L, Liu C, Li T, Zhang P, Zeng Y, Lei S, Chen P. Application of GOLD 2023 Initial Inhalation Therapy Recommendations in COPD patients: a real-world adherence and prognosis analysis. J Glob Health. 2025 Nov 28;15:04324. doi: 10.7189/jogh.15.04324. PMID 41313168
- BACKGROUNDZhou R, Qin Y, Hu S, Xu Y, Feng C. Effect of dual bronchodilators plus preoperative rehabilitation in operable LC & chronic obstructive pulmonary disease. Future Oncol. 2024 Dec;20(40):3471-3476. doi: 10.1080/14796694.2024.2430164. Epub 2024 Nov 28.