Clinical trial · Observational
Association Between Microplastic Exposure and the Pathological Progression of Gastric Carcinogenesis
Association of Microplastic Exposure With Pathological Stages of Gastric Mucosal Carcinogenesis: A Cross-Sectional Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this clinical trial is to explore the correlation between the level of microplastic exposure and the risk of gastric mucosal carcinogenesis, and to evaluate the strength of its effect as an independent risk factor. The main questions it aims to answer include: Does the level of microplastic exposure increase the risk of gastric mucosal carcinogenesis? Can the correlation between the level of microplastic exposure and gastric mucosal carcinogenesis, as well as the sources of high - risk microplastic exposure, be explored through a questionnaire on external microplastic exposure? Researchers will complete a design structured questionnaire and ask participants to fill it out carefully and truthfully to determine whether the level of microplastic exposure increases the risk of gastric mucosal carcinogenesis.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Carcinoma | Gastric Carcinoma | ONTOLOGY_EXACT | 0.98 |
| Gastric Precancerous Lesions | Gastric Neoplasm | PROBABILISTIC | 0.70 |
| Gastritis Chronic | — | UNRESOLVED | — |
| Intestinal Metaplasia | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (3)
- label
- Chronic non-atrophic gastritis
- description
- Patients diagnosed with chronic non-atrophic gastritis based on endoscopic and/or histopathological results
- label
- precancerous lesion
- description
- Patients with chronic atrophic gastritis, gastric intestinal metaplasia, and gastric intraepithelial neoplasia based on endoscopic and/or histopathological results
- label
- gastric cancer
- description
- patients with gastric cancer according to endoscopic and/or histopathological results
Primary outcomes (1)
- measure
- Correlation between external exposure levels of microplastics and three pathological stages of gastric mucosal carcinogenesis
- timeFrame
- 9 months
- description
- The investigators evaluated the correlation between external exposure to microplastics and the three pathological stages of gastric mucosal carcinogenesis based on the patients' final diagnosis results and the completed questionnaires they filled out.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Aged between 18 and 75 years old, gender is not restricted * Having a clear diagnosis result within the recent three months and being diagnosed with chronic non - atrophic gastritis, precancerous lesions of gastric cancer, or gastric cancer for the first time * Have clear Helicobacter pylori (Hp) test results * Be in normal mental state and able to independently complete the questionnaire survey Exclusion Criteria: * Patients with a history of malignant tumors in other parts * Patients who have previously undergone upper gastrointestinal surgery, chemotherapy, or radiotherapy * Patients with severe diseases of major organs such as the heart, lungs liver, and kidneys * Patients who are currently receiving psychological intervention or taking psychiatric drugs * Pregnant or lactating women * Patients with severe missing clinical data or questionnaire information * Refusing to sign the informed consent form
References
Publications (0)
Data not yet available