Clinical trial · Interventional
Preoperative Oncogeriatric Assessment in Patients Undergoing Hepatectomy
Impact of Preoperative Oncogeriatric Assessment in Elderly Patients Undergoing Surgery for Hepatectomy
NCT07537569CI-TRIAL-00108673recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 11, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260911-000001
Summary
Brief summary (as posted)
This study aims to bridge the gap between geriatric medicine and surgical oncology. The findings will provide valuable insights into optimizing perioperative care for older adults, enhancing surgical safety, and improving long-term recovery trajectories, thereby supporting a more patient-centered, multidisciplinary approach in the management of elderly patients undergoing hepatectomy
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Comprehensive Geriatric Assessment | — | UNRESOLVED | — |
| Hepatectomy | — | UNRESOLVED | — |
| Hepatic Malignancies | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Comprehensive Geriatric Assessment (CGA) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Comprehensive Geriatric Assessment (CGA) Group
- description
- Subjects undergo Comprehensive Geriatric Assessment (CGA) assessing frailty, functional status, cognition, comorbidities, nutritional and mental health status using validated tools (Fried Criteria, Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Charlson Comorbidity Index, Mini Nutritional Assessment, Geriatric Depression Scale). Subjects receive targeted preoperative interventions (nutritional support, prehabilitation, medical optimization, psychosocial support).
- interventionNames
- Other: Comprehensive Geriatric Assessment (CGA)
- type
- NO_INTERVENTION
- label
- Standard of Care Group
- description
- Subjects receive standard preoperative care including anesthesia, surgical procedures, and postoperative management according to institutional protocols
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged ≥ 70 years * Diagnosed hepatic malignancies requiring hepatectomy * Eligible for curative surgery as determined by multidisciplinary team * Ability to provide informed consent. Exclusion Criteria: * Ineligibility for surgery due to advanced disease or severe comorbidities * Severe cognitive impairment (MMSE score \< 18) * Refusal to participate
References
Publications (9)
- BACKGROUNDSchipa C, Luca E, Ripa M, Sollazzi L, Aceto P. Preoperative evaluation of the elderly patient. Saudi J Anaesth. 2023 Oct-Dec;17(4):482-490. doi: 10.4103/sja.sja_613_23. Epub 2023 Aug 18. PMID 37779566
- BACKGROUNDSteenblock J, Braisch U, Brefka S, Thomas C, Eschweiler GW, Rapp M, Metz B, Maurer C, von Arnim CAF, Herrmann ML, Wagner S, Denkinger M, Dallmeier D. Frailty index and its association with the onset of postoperative delirium in older adults undergoing elective surgery. BMC Geriatr. 2023 Feb 11;23(1):90. doi: 10.1186/s12877-022-03663-7. PMID 36774453
- BACKGROUNDKumar C, Salzman B, Colburn JL. Preoperative Assessment in Older Adults: A Comprehensive Approach. Am Fam Physician. 2018 Aug 15;98(4):214-220. PMID 30215973
- BACKGROUNDChen L, Zong W, Luo M, Yu H. The impact of comprehensive geriatric assessment on postoperative outcomes in elderly surgery: A systematic review and meta-analysis. PLoS One. 2024 Aug 28;19(8):e0306308. doi: 10.1371/journal.pone.0306308. eCollection 2024. PMID 39197016
- BACKGROUNDHoffmann TC, Del Mar C. Patients' expectations of the benefits and harms of treatments, screening, and tests: a systematic review. JAMA Intern Med. 2015 Feb;175(2):274-86. doi: 10.1001/jamainternmed.2014.6016. PMID 25531451
- BACKGROUNDNeuman MD, Silber JH, Magaziner JS, Passarella MA, Mehta S, Werner RM. Survival and functional outcomes after hip fracture among nursing home residents. JAMA Intern Med. 2014 Aug;174(8):1273-80. doi: 10.1001/jamainternmed.2014.2362. PMID 25055155
- BACKGROUNDOresanya LB, Lyons WL, Finlayson E. Preoperative assessment of the older patient: a narrative review. JAMA. 2014 May;311(20):2110-20. doi: 10.1001/jama.2014.4573. PMID 24867014