Clinical trial · Interventional
Comparison of Serratus Posterior Superior Intercostal Plane Block and Rhomboid Intercostal Block in Patients Undergoing Breast Cancer Surgery
Comparison of Serratus Posterior Superior Intercostal Plane Block and Rhomboid Intercostal Block for Postoperative Analgesia Following Breast Cancer Surgery With Axillary Lymph Node Dissection: A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) and Rhomboid Intercostal Block in patients undergoing Breast Cancer Surgery With Axillary Lymph Node Dissection. The primary outcome is Visual Analog Scale (VAS) during the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block performance time, block-related and systemic side effects (hematoma, pneumothorax, local anesthetic toxicity, vascular puncture, infection), Patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Lymph Node Dissection | — | UNRESOLVED | — |
| Mastectomy | — | UNRESOLVED | — |
| Postoperative Pain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Rhomboid intercostal plane block | Procedure | — | UNRESOLVED |
| Serratus posterior superior intercostal plane block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- SERRATUS POSTERİOR SUPERİOR İNTERCOSTAL PLANE BLOCK (SPSIPB)
- description
- PATİENTS İN THİS GROUP WİLL RECEİVE AN ULTRASOUND-GUİDED SERRATUS POSTERİOR SUPERİOR İNTERCOSTAL PLANE BLOCK(SPSIPB) FOR POSTOPERATİVE ANALGESİA FOLLOWİNG BREAST CANCER SURGERY
- interventionNames
- Procedure: Serratus posterior superior intercostal plane block
- type
- ACTIVE_COMPARATOR
- label
- RHOMBOİD İNTERCOSTAL BLOCK(RIB)
- description
- PATİENTS İN THİS GROUP WİLL RECEİVE AN ULTRASOUND-GUİDED RHOMBOİD İNTERCOSTAL BLOCK(RIB) FOR POSTOPERATİVE ANALGESİA FOLLOWİNG BREAST CANCER SURGERY
- interventionNames
- Procedure: Rhomboid intercostal plane block
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Female patients aged 18-65 years * ASA physical status I-III * Scheduled for elective breast cancer surgery with axillary lymph node dissection * Body mass index (BMI) between 18 and 35 kg/m² * Ability to understand and use the patient-controlled analgesia (PCA) device * Ability to provide written informed consent Exclusion Criteria: * Refusal to participate * Allergy to local anesthetics * Infection at the injection site * Coagulopathy or ongoing anticoagulant therapy * Chronic opioid use or opioid dependence * Severe hepatic or renal insufficiency * Pregnancy or breastfeeding * Cognitive impairment or inability to communicate pain scores * Body mass index (BMI) \<18 or \>35 kg/m²
References
Publications (0)
Data not yet available