Clinical trial · Interventional
Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer
NCT07518888CI-TRIAL-00118507ESCAPEnot yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 26, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260926-000001
Summary
Brief summary (as posted)
The purpose of this research study is to understand how a short session of a home-based bodyweight high-intensity interval training (HIIT) affects steroid hormone levels in men on active surveillance for low-grade prostate cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| High-Intensity Interval Training (HIIT) Exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Home-Based High Intensity Interval Training (HIIT) Exercise Session + Saliva Collection
- description
- Participants will complete a single supervised, online high intensity interval training (HIIT) exercise session with six bouts of 1-minute exercises performed at a moderate-to-high intensity lasting approximately 20 minutes. Saliva samples will be collected immediately prior to exercise, immediately following exercise, and 15 minutes post-exercise.
- interventionNames
- Behavioral: High-Intensity Interval Training (HIIT) Exercise
Primary outcomes (1)
- measure
- Protocol Completion Rate
- timeFrame
- From enrollment through completion of all study procedures (up to Day 1)
- description
- Protocol Completion Rate is defined as the proportion of enrolled participants who complete both the supervised home-based HIIT exercise session and return all scheduled saliva samples to the laboratory.
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Males 18 to 80 years old * Diagnosis of localized prostate cancer * Currently under active surveillance * Ability to perform moderate-to-high intensity physical activity as demonstrated by self-assessment using the Physical Activity Readiness Questionnaire (PAR-Q+) * Able to independently perform activities of daily living, without limitations in mobility * Ability to read, write, speak, and understand English * Able and willing to sign consent and comply with study requirements Exclusion Criteria: * Males currently receiving treatment for prostate cancer * Diagnosis of metastatic prostate cancer * Individuals with medical conditions contraindicating exercise * Uncontrolled cardiovascular or circulatory diseases, hypertension, and diabetes, as determined by the study doctor or treating physician * Ongoing use of medications affecting steroid metabolism * Unable to sign consent and/or comply with study requirements
References
Publications (0)
Data not yet available
No reference posted for this study.