Clinical trial · Interventional
Genetic Information for Families After Tumor Testing Study
Genetic Information for Families After Tumor Testing (GIFTT) Study
NCT07517666CI-TRIAL-00119672GIFTTenrolling by invitationN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to develop and implement a methodology of digital tools paired with telemedicine to improve cascade testing for clinically significant germline mutations among family members of children with cancer who have a pathogenic or likely pathogenic(P/LP) germline variant in a cancer predisposition gene.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Interactive Chatbot | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Single Arm
- description
- Genetic counseling via digital tools and telemedicine
- interventionNames
- Other: Interactive Chatbot
Primary outcomes (2)
- measure
- Uptake of digital pre-test chatbot
- timeFrame
- 6 months from consent
- description
- Participant completion of digital intervention as an alternative for pre-test counseling (yes/no)
- measure
- Uptake of genetic testing
- timeFrame
- 6 months from consent
- description
- Participant completion of genetic testing (yes/no)
Secondary outcomes (6)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Biological parent of a child enrolled in the ORIGen cohort (AEPI24N1) who has a confirmed P/LP germline variant in a CPG. * 18 years of age or older. * Speak and understand English. Exclusion Criteria: * Previous genetic testing for the familial variant. * Communication difficulties such as: * Uncorrected or uncompensated hearing and/or vision impairment. Patients who can successfully use clinical assistance devices are not excluded. * Uncorrected or uncompensated speech defects. Patients who can successfully use clinical assistance devices are not excluded. * Uncontrolled psychiatric/mental condition or severe physical, neurological or cognitive deficits rendering individual unable to understand study goals and tasks.
References
Publications (0)
Data not yet available
No reference posted for this study.