Clinical trial · Interventional
Electroacupuncture Plus 5-HT3 Receptor Inhibitor for PONV Prevention in High-Risk Patients Undergoing Thoracoscopic Lung Cancer Surgery
Electroacupuncture Combined With 5-HT3 Receptor Inhibitor for the Prevention of Postoperative Nausea and Vomiting in High-risk Patients Undergoing Thoracoscopic Surgery for Lung Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This prospective, randomized controlled study aims to evaluate the efficacy and safety of electroacupuncture combined with 5-HT3 receptor inhibitor for preventing postoperative nausea and vomiting (PONV) in high-risk patients undergoing thoracoscopic lung cancer surgery. The primary outcome is the incidence of PONV within 24 hours after surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| PONV | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Electroacupuncture | Other | — | UNRESOLVED |
| Prophylactic administration of dolasetron | Drug | — | UNRESOLVED |
| Sham electroacupuncture | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Electroacupuncture (EA) group
- description
- On the basis of receiving dolasetron and dexamethasone for preventing postoperative nausea and vomiting (PONV) during the perioperative period of video-assisted thoracoscopic surgery (VATS) for lung resection, the participants will receive electroacupuncture at 30 minutes before anesthesia induction and 4 hours after surgery.
- interventionNames
- Drug: Prophylactic administration of dolasetron
- Other: Electroacupuncture
- type
- SHAM_COMPARATOR
- label
- sham electroacupuncture (SA) group
- description
- On the basis of receiving dolasetron and dexamethasone for preventing postoperative nausea and vomiting (PONV) during the perioperative period of video-assisted thoracoscopic surgery (VATS) for lung resection, the participants will receive sham electroacupuncture at 30 minutes before anesthesia induction and 4 hours after surgery.
- interventionNames
- Drug: Prophylactic administration of dolasetron
- Other: Sham electroacupuncture
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥ 18 years; * American Society of Anesthesiologists (ASA) physical status I-III; * Body mass index (BMI) 18-30 kg/m²; * Scheduled for elective video-assisted thoracoscopic surgery (VATS) lobectomy, segmentectomy, or wedge resection; * Expected to receive postoperative opioid analgesia, with an Apfel risk score ≥ 3; * Normal pulmonary function, without severe cardiovascular, hepatic, or renal abnormalities; * No infection around the acupuncture sites; * Voluntary written informed consent provided by the subject. Exclusion Criteria: * Severe systemic diseases, such as cardiovascular, hepatic, or renal abnormalities, or poor pulmonary function; * Subjects with cognitive dysfunction or psychological disorders; * History of previous esophageal or gastric surgery; * Hypersensitivity to acupuncture or any study medications; * Severe infection or history of surgery around the acupuncture sites; * Pregnant or lactating women; * Long-term opioid use; * Conversion to open surgery; * Acupuncture treatment received within 1 month prior to enrollment.
References
Publications (0)
Data not yet available