Clinical trial · Interventional
Benefits of Early Collaboration Between Oncologists and Palliative Care Physicians in Cases of Unplanned Hospitalization for Patients With Metastatic Cancer
NCT07490106CI-TRIAL-00106372SPPCnot yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 18, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260918-000001
Summary
Brief summary (as posted)
This is a multicenter, national, interventional, cluster-randomized study, "stepped wedge" design. This study includes patients with metastatic or locally advanced digestive, gynecological, ENT, or sarcoma cancer, currently undergoing systemic palliative treatment and hospitalized on an unscheduled basis. The study will aim to evaluate the impact of early palliative care implementation for patients with metastatic or advanced cancer identified during an unplanned hospitalization.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Digestive Cancers | — | UNRESOLVED | — |
| ENT Cancer | — | UNRESOLVED | — |
| Gynaecologic Cancer | — | UNRESOLVED | — |
| Metastatic Cancer or Locally Advanced | — | UNRESOLVED | — |
| Sarcoma Metastatic | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Early integrated palliative care | Other | — | UNRESOLVED |
| Usual oncological care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Early integrated palliative care
- description
- Patients receive early integrated palliative care following an unplanned hospitalization for metastatic or advanced cancer. The intervention includes a palliative care consultation, consultation with the treating oncologist, and a multidisciplinary onco-palliative discussion to define a shared care strategy. Implementation of an early collaboration between oncologists and palliative care physicians. At the time of unplanned hospitalization, patients receive a palliative care consultation, a consultation with their oncologist, and a multidisciplinary discussion (onco-palliative meeting) to define a coordinated care strategy.
- interventionNames
- Other: Early integrated palliative care
- type
- ACTIVE_COMPARATOR
- label
- Usual oncological care
- description
- Patients receive standard oncological management without systematic early involvement of palliative care. Palliative care may be introduced according to usual clinical practice. Standard oncological care provided according to institutional practices without systematic early palliative care consultation at the time of unplanned hospitalization.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Subjects aged 18 years and older; * Diagnosed with metastatic or locally advanced digestive, gynecological, ENT, or sarcoma cancer; * Currently undergoing systemic palliative treatment (no prospect of cure); * Hospitalized on an unscheduled basis (i.e., unplanned hospitalization for scheduled oncology treatments); * Patient covered by the French social security system; * Informed consent, written and signed. Exclusion Criteria: * PS (WHO) = 4; * Patient receiving end-of-life care; * Patient opposed to the use of medical data for research purposes; * Person deprived of liberty or under guardianship; * Inability to undergo medical monitoring for the trial for geographical, social, or psychological reasons.
References
Publications (44)
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- BACKGROUNDMakker V, Colombo N, Casado Herraez A, Santin AD, Colomba E, Miller DS, Fujiwara K, Pignata S, Baron-Hay S, Ray-Coquard I, Shapira-Frommer R, Ushijima K, Sakata J, Yonemori K, Kim YM, Guerra EM, Sanli UA, McCormack MM, Smith AD, Keefe S, Bird S, Dutta L, Orlowski RJ, Lorusso D; Study 309-KEYNOTE-775 Investigators. Lenvatinib plus Pembrolizumab for Advanced Endometrial Cancer. N Engl J Med. 2022 Feb 3;386(5):437-448. doi: 10.1056/NEJMoa2108330. Epub 2022 Jan 19. PMID 35045221
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- BACKGROUNDPatel TL, Bouchal SR, Laing CM, Hubbard S. Diminuer le recours au service des urgences pour les patients externes presentant des symptomes aigus de cancer : revue integrative sur l'emergence des centres de soins d'urgence en cancerologie. Can Oncol Nurs J. 2021 Feb 1;31(1):36-50. doi: 10.5737/236880763113650. eCollection 2021 Winter. French. PMID 38919462
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- BACKGROUNDBraun, V., & Clarke, V. (2006). Using thematic analysis in psychology. Qualitative Research in Psychology, 3(2), 77-101. https://doi.org/10.1191/1478088706qp063oa