Clinical trial · Observational
Intradurale Spinal Tumors: Management and Treatment
Intradurale Spinal Tumors: Management and Treatment - A Retrospective Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Intradurale spinal tumors are rare neoplastic lesions that involve the spinal cord and surrounding structures and may cause neurological symptoms such as pain, motor deficits, sensory disturbances, and sphincter dysfunction. Surgical resection is often the primary treatment when feasible and may improve neurological outcomes and relieve spinal cord compression. This retrospective observational study aims to analyze the epidemiological and clinical characteristics of patients who underwent surgical treatment for intradural spinal tumors at the Neurosurgery Unit of Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria between 2022 and 2024. Clinical, radiological, and pathological data will be collected from electronic medical records, operative reports, and diagnostic imaging. The study will evaluate preoperative and postoperative neurological status using the McCormick functional scale, as well as postoperative complications and tumor recurrence. The results of this study may contribute to improving the understanding of the clinical management of intradural spinal tumors and identifying factors associated with surgical outcomes and patient prognosis.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Spinal Cord Neoplasms | Spinal Cord Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Spinal Neoplasms | Spinal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgical Resection of Intradural Spinal Tumors | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients With Intradural Spinal Tumors
- description
- Patients who underwent surgical treatment for intradural spinal tumors at the Neurosurgery Unit of Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo di Alessandria between 2022 and 2024. Clinical, radiological, and histopathological data were collected retrospectively from medical records to evaluate patient characteristics, neurological outcomes, postoperative complications, and tumor recurrence.
- interventionNames
- Procedure: Surgical Resection of Intradural Spinal Tumors
Primary outcomes (1)
- measure
- Neurological Functional Outcome Assessed
- timeFrame
- From preoperative assessment to last available follow-up (up to 24 months post-surgery)
- description
- Assessment of neurological functional status in patients undergoing surgical resection of intradural spinal tumors using the McCormick functional grading scale (Grade I: neurologically normal or mild deficit; Grade II: mild functional deficit, independent; Grade III: moderate deficit, limited independence; Grade IV: severe deficit, dependent; Grade V: paraplegia or quadriplegia). Preoperative and postoperative scores will be compared to evaluate changes in neurological function.
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients hospitalized at Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo di Alessandria (Neurosurgery Unit). * Patients who underwent surgical resection of an intradural spinal tumor. * Diagnosis consistent with intradural spinal tumors according to ICD-9 codes. * Availability of clinical, radiological, and surgical data in medical records. * Signed informed consent. Exclusion Criteria: * Incomplete medical records or missing clinical data required for the study. * Tumors with uncertain extradural extension identified during surgery. * Tumors arising from peripheral nerves.
References
Publications (0)
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