Clinical trial · Interventional
COMPARISON OF OBTURATOR NERVE BLOCK TECHNIQUES IN TURBT
COMPARISON OF THE EFFECT OF SUBPECTINEAL OBTURATOR NERVE BLOCK AND INTERFASCIAL OBTURATOR NERVE BLOCK ON ADDUKTOR MUSCLE SPASM IN PATIENTS WHO UNDERWENT TUR-BT OPERATION
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Bladder cancer is one of the most common cancers in older adults. The standard treatment for many bladder tumors is a surgical procedure called transurethral resection of bladder tumor (TUR-BT). During this operation, tumors located on the side wall of the bladder may trigger an involuntary leg movement known as the "obturator reflex." This reflex occurs when electrical stimulation during surgery activates the obturator nerve, causing sudden contraction of the inner thigh (adductor) muscles. Such muscle spasms can lead to serious complications, including incomplete tumor removal or bladder perforation. To prevent this reflex, anesthesiologists perform an obturator nerve block (ONB), a procedure in which local anesthetic medication is injected around the nerve to temporarily stop its function. With advances in ultrasound technology, different ultrasound-guided techniques have been developed to perform this nerve block more safely and effectively. There are two commonly used approaches. The first is the interfacial (distal) technique, in which two separate injections are performed to block the anterior and posterior branches of the obturator nerve. The second is the subpectineal (proximal) technique, in which the nerve is blocked with a single injection at a more proximal location, potentially using a smaller amount of local anesthetic. The purpose of this study was to compare these two ultrasound-guided techniques in patients undergoing TUR-BT surgery. The aim of this study was to compare the effectiveness and safety of the subpectineal and interfacial obturator nerve block techniques in preventing adductor muscle spasm during surgery. Sixty patients aged between 50 and 80 years who were scheduled for TUR-BT were randomly assigned to receive either the subpectineal or the interfacial obturator nerve block. The main outcome measured was the occurrence and severity of adductor muscle spasm during surgery. Secondary outcomes included the number of needle insertions, duration of anesthesia and surgery, and any complications related to the block. The hypothesis of this study was that the subpectineal technique would provide comparable effectiveness in preventing adductor muscle spasm compared with the interfacial technique while requiring fewer injections and a lower volume of local anesthetic. The results of this study may help determine the most effective and practical technique for preventing surgical complications during bladder tumor surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer | Malignant Bladder Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Interfacial Obturator Nerve Block | Procedure | — | UNRESOLVED |
| Subpectineal Obturator Nerve Block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Subpectineal Obturator Nerve Block
- description
- Participants in this arm received an ultrasound-guided subpectineal obturator nerve block prior to transurethral resection of bladder tumor. A single injection of 10 mL of 0.375% bupivacaine was administered into the fascial plane between the pectineus and obturator externus muscles to achieve proximal blockade of the obturator nerve.
- interventionNames
- Procedure: Subpectineal Obturator Nerve Block
- type
- ACTIVE_COMPARATOR
- label
- Interfacial Obturator Nerve Block
- description
- Participants in this arm received an ultrasound-guided interfacial obturator nerve block prior to transurethral resection of bladder tumor. Two separate injections of 10 mL of 0.375% bupivacaine were administered between the adductor longus and brevis muscles and between the adductor brevis and magnus muscles to block the anterior and posterior branches of the obturator nerve.
- interventionNames
- Procedure: Interfacial Obturator Nerve Block
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 50 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged between 50 and 80 years * Diagnosed with bladder tumor and scheduled for transurethral resection of bladder tumor (TURBT) * Classified as American Society of Anesthesiologists (ASA) physical status I-III * Provided written informed consent Exclusion Criteria: * Coagulopathy or anticoagulant therapy contraindicating regional anesthesia * Known allergy to local anesthetics * Infection at the injection site * Pre-existing neuromuscular disorder affecting lower extremities * Severe cardiac, hepatic, or renal dysfunction * Inability to provide informed consent
References
Publications (0)
Data not yet available