Clinical trial · Observational
Insights on Dissemination of Lung Cancer
NCT07476495CI-TRIAL-00105677LUCIDrecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In patients with resectable NSCLC treated with surgery alone or with surgery as part of a multimodal treatment; CTC, ctDNA, STAS, and lymph node micrometastasis levels will be evaluated to see if they are associated with recurrence patterns and long-term outcomes.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Oncology & Epidemiology & Lung Cancer | Lung Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Measurement and quantification of CTC and ctDNA
- timeFrame
- From enrollment to the end of study at 36 months
- description
- * CTC (Circulating Tumor Cells) using CellSearch® (FDA-cleared) number cells per 7.5 mL of whole blood * ctDNA (Circulating Tumor DNA) using NGS (Illumina platform) - Variant Allele Frequency VAF (%)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥ 18 years; * Preoperative diagnosis of resectable stage cIA-cIIIA NSCLC (adenocarcinoma or squamous cell carcinoma); * Patients deemed fit for surgical or multimodal treatment; * Informed consent obtained; * Treatment, including multimodal treatment, involving surgery. Exclusion Criteria: * Histology other than adenocarcinoma or squamous cell carcinoma; * Other neoplastic diseases concurrent with or undergoing treatment or treated with systemic therapies in the previous three years; * Age \<18 years; * No need for surgery.
References
Publications (0)
Data not yet available
No reference posted for this study.