Clinical trial · Interventional
Lidocaine IV Injection With Different Doses for Patients With Neuropathic Pain After Mastectomy
Comparative Study of Lidocaine IV Injection With Two Different Doses for Patients With Neuropathic Pain Who Undergoing Mastectomy for Cancer Breast
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
cancer has become the most common malignancy affecting women worldwide, and its incidence is increasing annually. According to the Global Cancer Observatory (GLOBOCAN) 2020 published by the International Agency for Research on Cancer of the World Health Organization, female breast cancer is the cancer with the highest number of new cases worldwide significant number of patients experiencing moderate to severe acute pain (30-50%) and developing chronic post-surgical pain (CPSP) (25-68%)
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neuropathic Pain Induced by Mastectomy | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Lidocaine | Drug | — | UNRESOLVED |
| Lidocaine 2% | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Lidocaine 2 mg/kg
- description
- Patients receive 2 mg/kg lidocaine IV injection over 30 minutes.
- interventionNames
- Drug: Lidocaine 2%
- type
- ACTIVE_COMPARATOR
- label
- Lidocaine 6 mg/kg
- description
- Patients receive 6 mg/kg lidocaine IV injection over 30 minutes
- interventionNames
- Drug: Lidocaine
Primary outcomes (1)
- measure
- To assess neuropathic pain scale
- timeFrame
- assessed at 0, 15, 30, 1 hour. 2 hours and 24 hours and 1 week after injection
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients ≥ 18years. * Females with neuropathic pain following mastectomy for cancer breast. * American Society of Anesthesiologists (ASA) physical status I-III. * Patients on other drugs with intolerable side effects. * Patients undergoing breast surgery Exclusion Criteria: * Patients with known hypersensitivity to lidocaine. * Patients with history of uncontrolled seizures. * Patients with second- or third-degree heart block. * Patients with altered cognitive dysfunction.
References
Publications (0)
Data not yet available