Clinical trial · Interventional
Improving Clinic Delivery of HIV-related Anal Health Services
Partnering to Enhance Anal Health Communication and HIV-related Evidence-based Services
NCT07464236CI-TRIAL-00113463PEACHES 2not yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This project will test ways to reduce stigma in healthcare settings so that more providers offer, and more patients receive, important anal sex-related HIV services, including anorectal sexually transmitted infection (STI) testing, preventive medications, and cancer screening. By evaluating these stigma-reduction strategies in eight clinics in the Mississippi Delta, a region with high rates of HIV and STIs, the research team will learn whether and how these approaches work to improve access to care. The results will help guide healthcare systems in using the most effective methods to reduce stigma, making it easier for people to get prevention services and improving public health.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anal Cancer Squamous Cell | — | UNRESOLVED | — |
| Chlamydia | — | UNRESOLVED | — |
| Gonorrhea | — | UNRESOLVED | — |
| HIV | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PEACHES 2.0 Implementation Strategies | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- PEACHES 2.0 Implementation Strategies
- interventionNames
- Behavioral: PEACHES 2.0 Implementation Strategies
Primary outcomes (1)
- measure
- Patient uptake of anorectal STI screening
- timeFrame
- Data will be collected monthly via the audit-and-feedback data dashboard. First data collection occurs just after month 1 of the Pre-Implementation period, continuing through Implementation and Maintenance periods, for a total of 36 months.
- description
- Clinics will extract deidentified patient level outcomes from the medical record system on a monthly basis. This data will be imported into an audit-and-feedback data dashboard developed by the PEACHES 2.0 team. For patient uptake of anorectal STI screening, the number of anorectal STI screening orders per month among all STI orders in that same month will be calculated, and the slopes across the three 12-month data collection periods: Pre-Implementation, Implementation, and Maintenance periods, will be compared.
Secondary outcomes (3)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria:
Staff participants ("Strategy Recipients" and "Strategy Recipients")
* employed at one of eight Coastal Family Health Center clinics at the time of the survey
* over age 18 years old
Patient participants ("Patients")
* accessing sexual health services at one of eight Coastal Family Health Center clinics in the last 12 months
* over 18 years old
Exclusion Criteria:
* Staff or patients who are unable to provide informed consent (e.g., significant cognitive impairment)
* Individuals currently incarcerated or in state custody
* Patients whose only visits are for non-HIV, non-STI issues and who do not meet the EMR-based eligibility criteria aboveReferences
Publications (20)
- BACKGROUNDFixsen, D. L., Naoom, S. F., Blase, K. A., Friedman, R. M., & Wallace, F. (2005). Implementation research: A synthesis of the literature. Louis de la Parte Florida Mental Health Institute at the University of South Florida (FMHI Publication #231).
- BACKGROUNDHuman Behaviour Change Project. (2025). Behaviour Change Intervention Ontology (BCIO). https://www.bciontology.org/learn
- BACKGROUNDWright AJ, Zhang L, Howes E, Veall C, Corker E, Johnston M, Hastings J, West R, Michie S. Specifying how intervention content is communicated: Development of a Style of Delivery Ontology. Wellcome Open Res. 2023 Oct 12;8:456. doi: 10.12688/wellcomeopenres.19899.1. eCollection 2023. PMID 39193088
- BACKGROUNDCho E, Lyon AR, Tugendrajch SK, Marriott BR, Hawley KM. Assessing provider perceptions of training: Initial evaluation of the Acceptability, Feasibility, and Appropriateness Scale. Implement Res Pract. 2022 Apr 5;3:26334895221086269. doi: 10.1177/26334895221086269. eCollection 2022 Jan-Dec. PMID 37091090
- BACKGROUNDKutner BA, Wu Y, Balan IC, Meyers K. "Talking About it Publicly Made Me Feel Both Curious and Embarrassed": Acceptability, Feasibility, and Appropriateness of a Stigma-Mitigation Training to Increase Health Worker Comfort Discussing Anal Sexuality in HIV Services. AIDS Behav. 2020 Jun;24(6):1951-1965. doi: 10.1007/s10461-019-02758-4. PMID 31858301
- BACKGROUNDKutner BA, Perry NS, Stout C, Norcini Pala A, Paredes CD, Nelson KM. The Inventory of Anal Sex Knowledge (iASK): A New Measure of Sexual Health Knowledge Among Adolescent Sexual Minority Males. J Sex Med. 2022 Mar;19(3):521-528. doi: 10.1016/j.jsxm.2021.12.011. Epub 2022 Jan 26. PMID 35090838
- BACKGROUNDKutner BA, Simoni JM, King KM, Goodreau SM, Norcini Pala A, Creegan E, Aunon FM, Baral SD, Rosser BRS. Does Stigma Toward Anal Sexuality Impede HIV Prevention Among Men Who Have Sex With Men in the United States? A Structural Equation Modeling Assessment. J Sex Med. 2020 Mar;17(3):477-490. doi: 10.1016/j.jsxm.2019.12.006. Epub 2020 Jan 10.