Clinical trial · Interventional
The Effect of Relaxation Breathing Exercise on Chemotherapy Induced Nausea and Vomiting
The Effect of Relaxation Breathing Exercise on Chemotherapy Induced Nausea and Vomiting in Patients With Hematological Malignancies
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Effect of Relaxation Breathing Exercise on Chemotherapy Induced Nausea and Vomiting in Patients With Hematological Malignancies ABSTRACT Background: Chemotherapy is widely used in the treatment of hematological malignancies despite it has important and difficult side effects in patients. Chemotherapy induced nausea and vomiting are among the most common side effects in patients and antiemetic drugs may not be always curative. Purpose: This research aimed to determine the effectiveness of relaxation breathing exercise on managing chemotherapy induced nausea and vomiting in patients with hematological malignancies undergoing chemotherapy. Method: A randomized controlled trial design was conducted with a total of selected sixty eight patients with hematological malignancies (34 intervention and 34 control participants) undergoing chemotherapy hospitalized in the hematology clinic of a Training and Research Hospital. The intervention group implemented relaxation breathing exercise three times a day with a standard treatment protocol and the control group only received routine drug treatment for chemotherapy induced nausea and vomiting. Nausea and vomiting were assessed by filling Rhodes Index of Nausea Vomiting and Retching (RINVR) for the first six days after the start of the chemotherapy. Results: Data collection process ended. Data analysis process is in progress. Conclusion: In this study the effectiveness of relaxation breathing exercise on chemotherapy related nausea and vomiting will be examined in patients with hematological malignancies. Keywords: Relaxation breathing exercise; Hematological malignancies; Chemotherapy; Nausea and vomiting
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hematological Malignancies | Hematopoietic and Lymphoid Cell Neoplasm | ALIAS | 0.90 |
| Nausea and Vomiting Chemotherapy-Induced | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Control group | Behavioral | — | UNRESOLVED |
| Relaxation breathing exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Relaxation breathing exercise intervention group
- interventionNames
- Behavioral: Relaxation breathing exercise
- type
- EXPERIMENTAL
- label
- Control group
- interventionNames
- Behavioral: Control group
Primary outcomes (1)
- measure
- Change from the start of the chemotherapy in the frequency and severity of nasea, vomiting and retching at 6 days.
- timeFrame
- From enrollment to the end of intervention at 6 days
- description
- Zero is equivalent to no nausea, no vomiting and no retching and 4 indicates the worst and unbearable nausea, vomiting and retching
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Aged 18 years or over with hematological malignancies * Undergoing chemotherapy * Not having any communication problems (able to read, write and speak Turkish. Exclusion Criteria: * Having psychiatric and mental problems * Receiving radiotherapy concurrent with chemotherapy, 3) Having respiratory distress * Having central nervous system involvement * Having Grade 3 or Grade 4 nausea and vomiting.
References
Publications (0)
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