Clinical trial · Interventional
Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery
Effectiveness and Safety of 6% Versus 8% Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Minor Surgery: A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery. The primary outcome is emergence agitation assessed using the Pediatric Anesthesia Emergence Delirium (PAED) scale. Secondary outcomes include hemodynamic parameters, induction time, recovery time, and adverse events.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chalazion | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Sevoflurane | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Sevoflurane 8% Group
- description
- Participants received 8% sevoflurane inhalation for anesthesia induction via face mask.
- interventionNames
- Drug: Sevoflurane
- type
- EXPERIMENTAL
- label
- Sevoflurane 6% Group
- description
- Participants received 6% sevoflurane inhalation for anesthesia induction via face mask.
- interventionNames
- Drug: Sevoflurane
Primary outcomes (1)
- measure
- PAED score
- timeFrame
- Within 30 minutes after recovery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Year
- Maximum age
- 6 Years
Show eligibility criteria text
Inclusion Criteria: * Children aged 1 to 6 years (12-72 months) * Scheduled to undergo minor ophthalmic surgery (e.g., chalazion excision) under general anesthesia * American Society of Anesthesiologists (ASA) physical status I * Assessed as suitable for inhalation anesthesia by anesthesiologists * Written informed consent obtained from parents or legal guardians Exclusion Criteria: * ASA physical status II or higher * Known hepatic or renal dysfunction * Congenital heart disease * History of malignant hyperthermia * Known allergy to sevoflurane * History of asthma or severe respiratory disease * Upper respiratory tract infection within the past 4 weeks * Anticipated difficult airway * Refusal of participation by parents or legal guardians
References
Publications (0)
Data not yet available