Clinical trial · Interventional
Transdiscal vs Paravertebral Neurolytic Splanchnic Nerve Block for Upper Abdominal Cancer Pain
Comparison of Transdiscal and Paravertebral Approaches for Neurolytic Splanchnic Nerve Block in the Treatment of Upper Abdominal Cancer Pain
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to compare the efficacy of fluoroscopy-guided paravertebral (PV) and transdiscal (TD) approaches for splanchnic nerve neurolysis in patients with upper abdominal cancer-related pain (e.g., gastric, pancreatic, and hepatic malignancies). Treatment response will be assessed using the Numerical Rating Scale (NRS), and the impact of both techniques on quality of life will be evaluated with the EORTC QLQ-C30 questionnaire.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Pain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| paravertebral splanchnic neurolysis | Procedure | — | UNRESOLVED |
| transdiscal splanchnic neurolysis | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- transdiscal splanchnic neurolysis group
- description
- Transdiscal splanchnic neurolysis for upper gastrointestinal malignancy pain
- interventionNames
- Procedure: transdiscal splanchnic neurolysis
- type
- ACTIVE_COMPARATOR
- label
- paravertebral splanchnic neurolysis group
- description
- Paravertebral splanchnic neurolysis for upper gastrointestinal malignancy pain
- interventionNames
- Procedure: paravertebral splanchnic neurolysis
Primary outcomes (1)
- measure
- Numerical rating scale (NRS)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Severe abdominal pain (NRS \> 6) due to upper intra-abdominal organ malignancies (such as gastric, pancreatic, or hepatic cancer). * Failure of pain control with conservative treatment modalities. Exclusion Criteria: * Presence of local anatomical variations * Localized or systemic infection involving the procedural site * Pregnancy * Coagulopathy * Presence of unstable psychiatric disorders
References
Publications (0)
Data not yet available