Clinical trial · Observational
Study of Risk Factors and Prediction of Blood Clots After Lung Cancer Surgery
Prospective Cohort Study on Risk Factors and Machine Learning-Based Prediction of Postoperative Venous Thromboembolism in Patients Undergoing Lung Cancer Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to learn about the risk factors and prediction of postoperative venous thromboembolism (VTE) in patients undergoing lung cancer surgery. The main question it aims to answer is: Which clinical, surgical, and laboratory factors are associated with the development of postoperative deep vein thrombosis (DVT) in lung cancer surgery patients, and can machine learning models accurately predict individual risk? Participants undergoing lung cancer surgery will be prospectively followed for 30 days after surgery. Perioperative clinical data, laboratory results, and imaging findings will be collected to identify VTE risk factors and to develop a predictive model.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Deep Vein Thrombosis (DVT) | — | UNRESOLVED | — |
| Lung Cancer (Diagnosis) | Malignant Lung Neoplasm | CURATED_EXACT | 0.85 |
| Venous Thromboembolism (VTE) | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Prospective Perioperative Data Collection | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- VTE Group
- description
- Adult patients undergoing lung cancer surgery who develop postoperative deep vein thrombosis (DVT) within 30 days. Perioperative clinical, laboratory, and imaging data will be collected to identify risk factors and build predictive models.
- interventionNames
- Other: Prospective Perioperative Data Collection
- label
- Non-VTE Group
- description
- Adult patients undergoing lung cancer surgery who do not develop postoperative DVT within 30 days. Perioperative clinical, laboratory, and imaging data will be collected for comparison with the VTE group.
- interventionNames
- Other: Prospective Perioperative Data Collection
Primary outcomes (1)
- measure
- Incidence of postoperative deep vein thrombosis (DVT) in lung cancer surgery patients
- timeFrame
- From the day of lung cancer surgery to 30 days postoperatively
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age ≥ 18 years 2. Patients undergoing surgical resection for lung cancer 3. Postoperative hospital stay ≥ 48 hours 4. Availability of perioperative clinical, laboratory, and imaging data 5. Willingness to provide informed consent and participate in 30-day follow-up Exclusion Criteria: 1. Pre-existing deep vein thrombosis (DVT) or pulmonary embolism (PE) before surgery 2. Preoperative or ongoing anticoagulation therapy for ≥ 2 weeks 3. Severe coagulation disorders or bleeding diseases 4. Severe hepatic, renal, or hematologic dysfunction, or uncontrolled systemic infection 5. Concurrent major organ surgery (e.g., cardiac, liver surgery) 6. Pregnancy or lactation 7. Incomplete postoperative follow-up data
References
Publications (0)
Data not yet available