Clinical trial · Observational
MRA Diameter as a Predictor for LLN Metastasis in Rectal Cancer.
Middle Rectal Artery Diameter as a Predictor for Lateral Lymph Node Metastasis in Rectal Cancer: A Predictive Model for Surgical Decision-Making.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to identify risk factors-including clinical and imaging indicators such as middle rectal artery (MRA) diameter-that may be associated with lateral lymph node metastasis (LLNM) in rectal cancer located below the peritoneal reflection, and to construct a corresponding predictive model.The main questions it aims to answer are: What factors are associated with clinically suspected lateral lymph node metastasis in rectal cancer below the peritoneal reflection? Can an effective predictive model be constructed based on these factors? Participants' clinical information has been collected for statistical analysis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Neoplasms | Rectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No Intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Clinically suspected LLNM
- description
- Patients with clinically suspected lateral lymph node metastasis.
- interventionNames
- Other: No Intervention
- label
- Clinically suspected non-LLNM
- description
- Patients without clinically suspected lateral lymph node metastasis.
- interventionNames
- Other: No Intervention
Primary outcomes (1)
- measure
- Independent Risk Factors for Clinically Suspected Lateral Lymph Node Metastasis (cLLNM)
- timeFrame
- At the time of preoperative assessment (Data collected retrospectively from January 2022 to December 2024).
- description
- Multivariable logistic regression analysis incorporating preoperative clinical and imaging variables to identify independent risk factors associated with clinically suspected lateral lymph node metastasis (cLLNM). Results are presented as odds ratios with 95% confidence intervals.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Age at diagnosis between 18 and 75 years * Pathological confirmation of rectal adenocarcinoma by endoscopic biopsy * Imaging confirmation that the tumor was located below the peritoneal reflection * Availability of rectal MRI scans providing detailed imaging of the pelvic region * Received treatment at The First Affiliated Hospital of Fujian Medical University between January 2022 and December 2024 Exclusion Criteria: * Pathological diagnosis of non-primary rectal malignancies * Previous treatment for rectal cancer with chemotherapy, radiotherapy, or surgery, with the current presentation indicating recurrence * Incomplete rectal MRI data or poor image quality affecting interpretation * Incomplete medical or clinical records. Ultimately, 690 patients were included in the final analysis
References
Publications (0)
Data not yet available