Clinical trial · Interventional
Robot-Assisted Radical Prostatectomy: the HOOD Technique Versus Standard Anterior Reconstruction
Early Functional Outcomes After Robot-Assisted Radical Prostatectomy: A Prospective Comparison of the HOOD Technique Versus Standard Anterior Reconstruction
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This prospective, non-randomized cohort study included consecutive patients undergoing robotic-assisted laparoscopic radical prostatectomy (RARP) between January 2024 and January 2026 following ethics committee approval. Patients with clinically localized prostate cancer eligible for bilateral nerve-sparing surgery were enrolled. Two surgical techniques-anterior-posterior reconstruction (APR) and the HOOD technique-were compared. All procedures were performed by a single high-volume surgeon at a tertiary referral center. The primary endpoint was early urinary continence recovery, assessed at catheter removal and at 3, 6, and 12 weeks postoperatively. Secondary outcomes included postoperative complications, positive surgical margin rates, and early oncological outcomes.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer (Adenocarcinoma) | Malignant Prostate Neoplasm | CURATED_EXACT | 0.85 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Prostatectomy with anterior-posterior renconstruciton | Procedure | — | UNRESOLVED |
| Prostatectomy with HOOD techinque | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- HOOD technique
- interventionNames
- Procedure: Prostatectomy with HOOD techinque
- type
- ACTIVE_COMPARATOR
- label
- Anterior-Posterior reconstruction
- interventionNames
- Procedure: Prostatectomy with anterior-posterior renconstruciton
Primary outcomes (1)
- measure
- Functional outcomes
- timeFrame
- 3 weeks , 6 weeks and 12 weeks after surgery.
- description
- The Urinary continance recovery rates at the catheter removal, and subsequently at 3 weeks , 6 weeks and 12 weeks after surgery.
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 40 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * life expectancy \>10 years, * clinically organ confined disease (cT1-cT2), * biopsy ISUP GG ≤3, * total serum prostate-specific antigen (PSA) ≤10 ng/ml * normal preoperative continence and potency Exclusion Criteria: * high risk prosatate cancer * cN1 * M1 prostate cancer (according to preoperative GA68 PSMA PET CT) * pre-existing urinary incontinence, * previous prostatic, urethral, bladder neck surgery * neoadjuvant therapy * prior pelvic radiotherapy
References
Publications (8)
- BACKGROUNDMandel A, Choudhary M, Tillu N, Maheshwari A, Kolanukuduru K, Wagaskar V, Tewari A. Hood Technique for Radical Prostatectomy. J Endourol. 2025 Mar;39(S1):S35-S38. doi: 10.1089/end.2024.0303. PMID 40100831
- BACKGROUNDTurkolmez K, Akpinar C, Kubilay E, Suer E. Retzius-Sparing vs Modified Anatomical Structure Preserving and Retzius-Repairing Robotic-Assisted Radical Prostatectomy: A Prospective Randomized Comparison on Functional Outcomes with a 1-Year Follow-Up. J Endourol. 2022 Sep;36(9):1214-1222. doi: 10.1089/end.2022.0073. Epub 2022 Jun 2. PMID 35546454
- BACKGROUNDTewari AK, Bigelow K, Rao S, Takenaka A, El-Tabi N, Te A, Vaughan ED. Anatomic restoration technique of continence mechanism and preservation of puboprostatic collar: a novel modification to achieve early urinary continence in men undergoing robotic prostatectomy. Urology. 2007 Apr;69(4):726-31. doi: 10.1016/j.urology.2006.12.028. PMID 17445659
- BACKGROUNDStudent V Jr, Vidlar A, Grepl M, Hartmann I, Buresova E, Student V. Advanced Reconstruction of Vesicourethral Support (ARVUS) during Robot-assisted Radical Prostatectomy: One-year Functional Outcomes in a Two-group Randomised Controlled Trial. Eur Urol. 2017 May;71(5):822-830. doi: 10.1016/j.eururo.2016.05.032. Epub 2016 Jun 6. PMID 27283216
- BACKGROUNDPorpiglia F, Bertolo R, Manfredi M, De Luca S, Checcucci E, Morra I, Passera R, Fiori C. Total Anatomical Reconstruction During Robot-assisted Radical Prostatectomy: Implications on Early Recovery of Urinary Continence. Eur Urol. 2016 Mar;69(3):485-95. doi: 10.1016/j.eururo.2015.08.005. Epub 2015 Aug 19. PMID 26297603
- BACKGROUNDMather JS. Impossible direct laryngoscopy in achondroplasia. A case report. Anaesthesia. 1966 Apr;21(2):244-8. doi: 10.1111/j.1365-2044.1966.tb02607.x. No abstract available. PMID 5956576
- Heesakkers J, Farag F, Bauer RM, Sandhu J, De Ridder D, Stenzl A. Pathophysiology and Contributing Factors in Postprostatectomy Incontinence: A Review. Eur Urol. 2017 Jun;71(6):936-944. doi: 10.1016/j.eururo.2016.09.031. Epub 2016 Oct 6.