the Efficacy of Ivermectin Alone or With Microneedling in Treatment of Cutaneous Warts.

To compare between the efficacy and safety of topical ivermectin alone, microneedling with topical ivermectin and topical salicylic acid in treatment of cutaneous warts. topical ivermectin 1% will be applied on warts whole night clinical assessment will be done every 2 weeks Microneedling will be performed on the lesion using a microneedling pen type device with a 1-cm tip diameter at a 2-mm depth setting for 2-3 minutes until pinpoint bleebing occurs 1 mL of topical ivermectin 1% will be applied on to the wart tissue. Sessions: Sessions will be performed every 2 weeks until complete cure or for maximum 6 sessions (total 3 month)

Sex

All

Minimum age

11 Years

Maximum age

80 Years

Inclusion Criteria:

* patients with cutaneous non genital warts aged 11:80 y.
* No concurrent systemic or topical treatment of warts

Exclusion Criteria:

* Genital warts.

  * Pregnancy and lactation.
  * History of any bleeding, clotting disorder or using anticoagulants
  * Chronic systemic diseases such as chronic renal failure, hepaticinsufficiency, and cardiovascular disorders.
  * patients who received any treatment for warts in the last month before the study.
  * Patients with history of neuropathy or peripheral ischemia.
  * Patients with signs of inflammation or infection.
  * Patients with history of a serious systemic or anaphylactic reaction or allergy to ivermectin.

• BACKGROUNDMehta N. Case study of oral ivermectin in patients with cutaneous warts. J Cardiovasc Dis Res. 2024;15(12):6438-46