Clinical trial · Interventional
Total Laparoscopic vs Open Pancreaticoduodenectomy for the Treatment of Periampullary Adenocarcinomas
NCT07388082CI-TRIAL-00103838completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Laparoscopic pancreaticoduodenectomy (LPD), a surgical option for nonpancreatic periampullary adenocarcinoma (NPPA), is a complex procedure that has become increasing popular. However, there is no consensus as to whether this technique should be performed routinely. Our aim was to evaluate the outcomes of LPD compared with open pancreaticoduodenectomy (OPD).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Periampullary Carcinoma | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional open pancreaticoduedectomy | Procedure | — | UNRESOLVED |
| Total laparoscopic pancreaticoduedectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- conventional open pancreaticoduedectomy
- description
- 15 patients underwent conventional open pancreaticoduedenctomy
- interventionNames
- Procedure: Conventional open pancreaticoduedectomy
- type
- ACTIVE_COMPARATOR
- label
- Total laparoscopic pancreaticoduedectomy
- description
- 15 patients underwent total laparoscopic pancreaticoduedectomy
- interventionNames
- Procedure: Total laparoscopic pancreaticoduedectomy
Primary outcomes (1)
- measure
- The incidence of pancreatic fistula after laparoscopic pancreaticoduodenectomy in comparison to open surgery
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * • Body mass index \<28.0 kg/m2. * Ampullary tumors, duodenal tumors restricted to the second part of the duodenum, or lower common bile duct tumors. * Carefully confirmed resectability of the tumors based on preoperative radiology conducted by experienced radiologists and surgeons. Exclusion Criteria: * • Patients with \>180 degrees superior mesenteric artery encasement * Any celiac abutment. * Unreconstructable superior mesenteric vein/portal occlusion" Aortic invasion or encasement. * A history of previous upper abdominal surgery. * Tumors extending to the uncinate. * Severe cardiorespiratory comorbidities.
References
Publications (1)
- RESULTPaniccia A, Schulick RD, Edil BH. Total Laparoscopic Pancreaticoduodenectomy: A Single-Institutional Experience. Ann Surg Oncol. 2015 Dec;22(13):4380-1. doi: 10.1245/s10434-015-4450-2. Epub 2015 Apr 18. PMID 25893407