Clinical trial · Observational
Correlation of Dermoscopic Findings With Histopathological Features and Invasion Depth in Cutaneous Squamous Cell Carcinoma
Correlation of Invasion Depth and Histopathological Features With Dermoscopic Findings in Cutaneous Squamous Cell Carcinoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a retrospective study including patients diagnosed with cutaneous squamous cell carcinoma between 2016 and 2025. Demographic, clinical, histopathological, and dermoscopic data were obtained from hospital records. Dermoscopic images taken with the FotoFinder dermoscope were independently evaluated by two dermatologists in a blinded manner. In addition, images were labeled using computer software and analyzed to measure the proportion of specific dermoscopic structures within the total lesion area. These quantitative data were used to examine the relationship between dermoscopic features and histopathological findings.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cutaneous Squamous Cell Cancer | Squamous Cell Carcinoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Cutaneous Squamous Cell Carcinoma Patients
- description
- This cohort includes patients diagnosed with cutaneous squamous cell carcinoma between 2016 and 2025 who underwent total excision and had available clinical, dermoscopic, and histopathological data in hospital records. No additional interventions were performed as part of the study.
Primary outcomes (1)
- measure
- Correlation between dermoscopic features and tumor invasion depth
- timeFrame
- Retrospective analysis of records from 2016 to 2025
- description
- The association between predefined dermoscopic features and histopathological tumor invasion depth will be evaluated using quantitative and qualitative dermoscopic assessments.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria:Age between 18 and 100 years at the time of diagnosis Histopathologically confirmed cutaneous squamous cell carcinoma Lesions that underwent total surgical excision Histopathology reports including both tumor differentiation grade and invasion depth Availability of dermoscopic images obtained prior to excision Dermoscopic images of sufficient quality for evaluation and image analysis - Exclusion Criteria: Lesions that received any prior treatment, including radiotherapy, chemotherapy, cryotherapy, or other destructive or topical treatments before excision Incomplete clinical, dermoscopic, or histopathological data Poor-quality dermoscopic images not suitable for reliable evaluation or segmentation \-
References
Publications (0)
Data not yet available