Clinical trial · Observational
Fertility Outcomes In Young Breast Cancer Patients And Their Prognosis And Offspring Health
NCT07376681CI-TRIAL-00101903enrolling by invitationClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to clarify the fertility status of young breast cancer patients, verify the independent impact of fertility behavior on the prognosis of patients with different molecular types, and evaluate the association between treatment regimens and offspring health.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Fertility | — | UNRESOLVED | — |
| Prognosis | — | UNRESOLVED | — |
| Young People | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (4)
- measure
- The overall-surviva(OS) period of childbirth after diagnosis
- timeFrame
- About 2 years after the start of the research.
- description
- The starting time of OS regarded as after completing the childbearing behavior.Death is regarded as the end time of OS.
- measure
- The disease-free survival(DFS) period of childbirth after diagnosis
- timeFrame
- About 2 years after the start of the research
- description
- The starting time of DFS is regarded as after completing the childbearing behavior.Repase or distant metastasis is regarded as the end time of DFS.
- measure
- The growth and development of offspring
- timeFrame
- About 2 years after the start of the research
- description
- The growth and development of young breast cancer patients after diagnosis. By collecting their height, weight and other data, using the Lambda-Mu-Sigma method recommended by WHO, the obtained data is fitted to the offspring growth curve of young breast cancer patients and compared with the standard curve, in order to evaluate whether the patients' offspring grows abnormally.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: Only subjects who meet all of the following inclusion criteria can be enrolled in this trial: 1. Female patients diagnosed with breast cancer aged ≤ 40 years; 2. Patients with pathologically confirmed breast cancer, and TNM stage 0-III, the disease is in a stable or progressive state; 3. Complete medical records and clinical follow-up data were available. Informed consent. Exclusion Criteria: Anyone who has one of the following conditions cannot be included in this trial: 1. Female patients with a diagnosis age\>40 years; 2. Stage IV breast cancer at first diagnosis; 3. The presence of other reproductive system diseases caused by oligomenorrhea or amenorrhea and infertility; Loss of clinical data or loss to follow-up.
References
Publications (0)
Data not yet available
No reference posted for this study.