Clinical trial · Interventional
Clear Cell Chondrosarcoma in Italy
Clear Cell Chondrosarcoma in Italy: Insights Into Radiological, Clinical and pathologicaL Features, With Emphasis on Prognosis (CIRCLE)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Clear cell chondrosarcoma of bone is considered a low-grade malignant tumor in the last WHO classification of soft tissue and bone tumors; however, it is reported that recurrences and metastasis can occur. Considering the uncertain prognosis of this rare tumor, with some cases that historically seems to pursue a bad prognosis, we decided to collect all the Italian cases of clear cell condrosarcoma, in order to better understand its natural history and prognosis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chondrosarcoma | Chondrosarcoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Molecular studies | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Patients
- description
- Patients with a diagnosis of clear cell chondrosarcoma
- interventionNames
- Genetic: Molecular studies
Primary outcomes (1)
- measure
- Prognostic accuracy
- timeFrame
- At baseline
- description
- Ability of the model to predict overall survival, measured by AUC/C-index
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Male and female patients with diagnosis of clear cell chondrosarcoma and chondrosarcoma with a clear cell component treated from 01 Jan 1982 to 31 Dec 2023 * Information available (date of primary tumor diagnosis, local treatments, systemic treatment, response to systemic treatment, date of progression) and date and status at last follow-up * Imaging studies available for revision * Histological slides available for revision Exclusion Criteria: * \- Diagnosis different from clear cell chondrosarcoma or chondrosarcoma with a clear cell component; * Absence of radiological and/or clinical data
References
Publications (0)
Data not yet available