Clinical trial · Interventional
Haemorrhoidectomy With vs Without Lateral Internal Sphincterotomy
Open Haemorrhoidectomy Combined With Lateral Internal Sphincterotomy Versus Conventional Haemorrhoidectomy: A Prospective Randomized Comparative Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Hemorrhoids are a common anorectal condition that often require surgical treatment in advanced stages. Open hemorrhoidectomy is effective but is frequently associated with significant postoperative pain and early bleeding. Increased anal sphincter spasm after surgery is believed to be a major contributor to these complications. This study evaluates whether adding lateral internal sphincterotomy (LIS) to conventional open hemorrhoidectomy reduces postoperative pain and bleeding. A total of 120 adult patients with Grade III or IV hemorrhoids were randomized to undergo either open hemorrhoidectomy with LIS or open hemorrhoidectomy alone. Postoperative pain was assessed using a visual analogue scale, and postoperative bleeding was recorded at 24 hours, 48 hours, one week, and two weeks after surgery. The results of this trial aim to determine whether the addition of LIS provides better short-term recovery and improved postoperative outcomes compared with standard hemorrhoidectomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Grade III and IV Hemorrhoids | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional Hemorrhoidectomy | Procedure | — | UNRESOLVED |
| Hemorrhoidectomy With LIS | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Hemorrhoidectomy With LIS
- description
- Patients undergo open hemorrhoidectomy combined with lateral internal sphincterotomy to reduce postoperative pain and anal sphincter spasm.
- interventionNames
- Procedure: Hemorrhoidectomy With LIS
- type
- ACTIVE_COMPARATOR
- label
- Conventional Hemorrhoidectomy
- description
- Patients undergo standard open hemorrhoidectomy without lateral internal sphincterotomy.
- interventionNames
- Procedure: Conventional Hemorrhoidectomy
Primary outcomes (1)
- measure
- Postoperative Pain
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Adults aged 18 to 70 years * Patients diagnosed with grade III or IV hemorrhoids * Patients scheduled for open hemorrhoidectomy * Patients able to provide informed consent Exclusion Criteria: * Patients with inflammatory bowel disease * Patients with anal fissure, fistula, or anorectal malignancy * Patients with previous anorectal surgery * Patients with bleeding or coagulation disorders * Patients unfit for surgery or general or spinal anesthesia
References
Publications (1)
- DERIVEDAlsalaumy AHA. Open haemorrhoidectomy combined with lateral internal sphincterotomy versus conventional haemorrhoidectomy: a prospective randomized comparative study. BMC Surg. 2026 Apr 17;26(1):362. doi: 10.1186/s12893-026-03714-5. PMID 41992176