Clinical trial · Observational
Prospective Familial Registry for Pancreas Research
Prospective Familial Cohort for Pancreas Research
NCT07358208CI-TRIAL-00101366PARTNERenrolling by invitationClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this research is to develop a resource registry of individuals currently without pancreatic cancer but are members of a kindred with two or more blood-related family members with pancreas cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Family History of Pancreas Cancer | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- Family history of pancreas cancer
- description
- Prospective cohort of individuals who do not have pancreas cancer but are members of a kindred with two or more blood-related family members with pancreas cancer, or with at least one blood-related family member with pancreas cancer and one relative who carries a variant in a gene known to be associated with pancreatic cancer.
Primary outcomes (2)
- measure
- To establish a prospective cohort of individuals from pancreas cancer families
- timeFrame
- 25 years
- description
- To establish and actively follow a resource registry of individuals currently without pancreatic cancer but are members of a kindred with two or more blood-related family members with pancreas cancer.
- measure
- Change in health
- timeFrame
- 25 years
- description
- Participants will be asked to complete a health questionnaire every 2 years to ascertain new cancer diagnosis in the subject and in first-degree relatives.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. An individual who was previously enrolled in Mayo Clinic IRB # 1197-00, 354-06, 355-06, or 19-010791 2. Is age 18 years or older. 3. Has a valid United States mailing address. 4. Has at least two blood-related relatives who have had pancreas cancer or has a blood-relative with pancreatic cancer and that relative carries a known germline mutation in APC, ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STK11, TP53 or mutations in other genes known to be associated with pancreatic cancer. Exclusion Criteria: 1. An individual who is a prison inmate 2. An individual who is not compos mentis (of sound mind, memory, and understanding), and not able to give consent. 3. Has personal history of pancreas cancer.
References
Publications (0)
Data not yet available
No reference posted for this study.