Clinical trial · Interventional
Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy
Comparing Different Techniques of Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy: A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The current study is a multiple-arm, single blinded, and controlled randomized trial. It will be conducted in two gynecological endoscopy centers: • ElShatby University Hospital, a tertiary level hospital in Alexandria, Egypt. • Al-Madina Women Hospital, A specialized hospital of Obstetrics and Gynecology, Alexandria, Egypt. Patient selection: women with uterine leiomyomata and planning for laparoscopic myomectomy will be assessed for eligibility then will be enrolled in the trial according to the following inclusion and exclusion criteria, after providing a written informed consent of participation. Outcome variables of the study: The primary outcome is intraoperative blood loss and the change in postoperative hemoglobin. The secondary outcomes of this study are the operative time of performing uterine arteries occlusion and the postoperative ovarian reserve.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Myomectomy | — | UNRESOLVED | — |
| Myomectomy; Surgical Blood Loss | — | UNRESOLVED | — |
| Uterine Fibroids (Leiomyoma) | Uterine Corpus Leiomyoma | ALIAS | 0.85 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bipolar coagulation of uterine arteries | Procedure | — | UNRESOLVED |
| Laparoscopic myomectomy only | Procedure | — | UNRESOLVED |
| Temporary clipping of uterine artery | Procedure | — | UNRESOLVED |
| Temporary occlusive suturing of uterine artery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- ACTIVE_COMPARATOR
- label
- Temporary clipping of uterine arteries
- interventionNames
- Procedure: Temporary clipping of uterine artery
- type
- ACTIVE_COMPARATOR
- label
- Temporary occlusive suturing of uterine artery
- interventionNames
- Procedure: Temporary occlusive suturing of uterine artery
- type
- ACTIVE_COMPARATOR
- label
- Bipolar coagulation of uterine arteries
- interventionNames
- Procedure: Bipolar coagulation of uterine arteries
- type
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: * women with uterine fibroids and complaining of either abnormal uterine bleeding, infertility, urinary or rectosigmoid pressure manifestations. * Fibroid size from 3 - 10 cm in diameter and with * a maximum number of 3 fibroids. Exclusion Criteria: * contraindication to pneumoperitoneum and laparoscopy, * patients with BMI \> 30 kg/m2, * history of midline abdominal incisions, * women with history of prior ovarian surgery, * women with history of hormonal treatment for the last 3 months before surgery, * women who are not good candidate for myomectomy and who would benefit more from hysterectomy such as, women with multiple ≥ 4 leiomyomata, associated adenomyosis, recurrent fibroids after myomectomy. * suspected endometrial malignancy or suspected leiomyosarcoma features on ultrasound and/or MRI. * Submucous fibroids who will undergo hysteroscopic myomectomy beside the laparoscopic surgery.
References
Publications (1)
- DERIVEDShoukry A, Aboali OA, Abdelquader MF, Gouda AMH. Comparing different techniques of uterine artery occlusion during laparoscopic myomectomy: a randomized controlled trial. BMC Womens Health. 2026 Aug 25;26(1):428. doi: 10.1186/s12905-026-04799-z. PMID 42649498