Clinical trial · Observational
Speech-based AI-driven Diagnostics and Rehabilitation for Oral and Oropharyngeal Cancer.
A Preliminary Study on the Phonetics of Resonance and Articulation Disorders Caused by Defects of the Oral and Maxillofacial Speech Organs and Speech Therapy
NCT07347899CI-TRIAL-00101040speech omicscompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Participants diagnosed with oral cancer, oropharyngeal cancer, or oral potentially malignant lesions, as well as healthy controls, had their speech audio recordings collected for the development and validation of AI-driven models for diagnosis and prognosis prediction of oral cancer and oropharyngeal cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Oral Cancer | Malignant Lip and Oral Cavity Neoplasm | CURATED_BROADER | 0.80 |
| Oropharyngeal Cancer | Malignant Oropharyngeal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- healthy control and oral potentially malignant lesion
- description
- Speakers with oral potentially malignant lesions or healthy status
- label
- oral cancer and oropharyngeal cancer
- description
- Patients diagnosed with oral cancer or oropharyngeal cancer
Primary outcomes (1)
- measure
- AUC value
- timeFrame
- From enrollment to the report of surgical pathology，up to two weeks.
- description
- Area under the receiver operating characteristic curve (AUC) for discriminating OC/OPC from healthy controls
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * diagnosed as having OC or OPC regardless of concrete pathological subtype (e.g., epithelial, adenoid, odontogenic) * without a history of other tumor-related treatment before the initial evaluation, such as radiotherapy and chemotherapy * native Chinese speakers Exclusion Criteria: * hearing impairment * history of stuttering, cerebrovascular accident, brain trauma, neurodegenerative diseases * severe dental or maxillofacial deformity * cleft lip, cleft palate, and related post-treatment status * severe cardiology conditions, breathing/pulmonology disorders, psychiatric disorders or other illnesses preventing patients from receiving standard surgery
References
Publications (0)
Data not yet available
No reference posted for this study.