Clinical trial · Interventional
Feasibility and Effects of Home-based Physical Activity Intervention in Patients With Breast Cancer in Indonesia
Move to Improve: Investigating the Feasibility of Embedding Physical Activity Into Routine Breast Cancer Care in Indonesia
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical trial is to learn the impact and implementation of home-based aerobic and resistance training for patients with breast cancer in Indonesia. The main questions it aims to answer are: * Does the home-based aerobic and resistance training improve physical fitness, fatigue, and quality of life of patients with breast cancer? * Are the benefits of aerobic and resistance training mediated by inflammatory level changes? * What are the barriers and facilitators in implementing the home-based aerobic and resistance training? * Is the home-based aerobic and resistance training feasible to be implemented in Indonesia's setting? To answer those questions, participants will: * Conduct home-based aerobic and resistance training with supervision. * Visit the hospital once every 4 weeks for their routine visits. * Undergo physical fitness test before and after 12 weeks using treadmill test, as well as interviews to assess fatigue, quality of life, and intervention acceptability. * Keep a diary to record the aerobic and resistance training at home. * Undergo routine monitoring by phone every week with the research team.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Neoplasms | Breast Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Physical Fitness | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 12weeks of home-based aerobic (pedometer-driven walking) and resistance training using therapeutic bands | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Physical activity intervention
- interventionNames
- Behavioral: 12weeks of home-based aerobic (pedometer-driven walking) and resistance training using therapeutic bands
Primary outcomes (3)
- measure
- Physical fitness
- timeFrame
- Baseline and post-intervention (12 weeks)
- description
- Physical fitness was measured using a submaximal treadmill test with the modified Bruce protocol. Treadmill speed and inclination were automatically increased every 3 min (test stage). The test was terminated when participants reached volitional fatigue. Physical fitness was classified as low, fair, average, and good, based on patients' age, treadmill test duration, and predicted VO2peak.
- measure
- Fatigue
- timeFrame
- Baseline and post-intervention (12 weeks)
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 17 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with stage I-III hormone-receptor positive breast cancer * Eastern Cooperative Oncology Group (ECOG) score ≤1 * Had completed primary treatment (e.g., surgery, chemotherapy, and radiotherapy), except for hormonal treatment * Within 5 years of diagnosis * Able to perform moderate-intensity physical activity as determined by their oncologist and care team * Able to read and write in Indonesian * Willing to provide written informed consent. Exclusion Criteria: * Had an ejection fraction of \<50% * Evidence of cardiac disease, severe musculoskeletal problems, or other contraindications for exercise.
References
Publications (6)
- BACKGROUNDLeite VF, Cecatto RB, Battistella LR, de Brito CMM. Establishing a Cancer Rehabilitation Service in a Middle-Income Country: an Experience from Brazil. Curr Phys Med Rehabil Rep. 2022;10(4):339-344. doi: 10.1007/s40141-022-00373-4. Epub 2022 Nov 28. PMID 36466557
- BACKGROUNDBatalik L, Winnige P, Dosbaba F, Vlazna D, Janikova A. Home-Based Aerobic and Resistance Exercise Interventions in Cancer Patients and Survivors: A Systematic Review. Cancers (Basel). 2021 Apr 15;13(8):1915. doi: 10.3390/cancers13081915. PMID 33921141
- BACKGROUNDde Jesus Leite MAF, Puga GM, Arantes FJ, Oliveira CJF, Cunha LM, Bortolini MJS, Penha-Silva N. Effects of combined and resistance training on the inflammatory profile in breast cancer survivors: A systematic review. Complement Ther Med. 2018 Feb;36:73-81. doi: 10.1016/j.ctim.2017.11.023. Epub 2017 Dec 1. PMID 29458936
- BACKGROUNDLahart IM, Metsios GS, Nevill AM, Carmichael AR. Physical activity for women with breast cancer after adjuvant therapy. Cochrane Database Syst Rev. 2018 Jan 29;1(1):CD011292. doi: 10.1002/14651858.CD011292.pub2. PMID 29376559
- BACKGROUNDMcNeely ML, Campbell KL, Rowe BH, Klassen TP, Mackey JR, Courneya KS. Effects of exercise on breast cancer patients and survivors: a systematic review and meta-analysis. CMAJ. 2006 Jul 4;175(1):34-41. doi: 10.1503/cmaj.051073. PMID 16818906
- DERIVEDAstari YK, Hutajulu SH, Fitriani Z, Mozhaf MDLQ, Paramita DK, Wibowo RA, Sofia NA, Hartopo AB, Hardianti MS, Purwanto I, Burke S. The changes of inflammatory biomarkers after a 12-week home-based aerobic and resistance exercise intervention in breast cancer survivors. BMC Res Notes. 2026 Mar 28;19(1):208. doi: 10.1186/s13104-026-07764-z. PMID 41904552