Clinical trial · Interventional
Cognition Assessment and REhabilitation in Virtual Reality for Patients With Cancer
Cognition Assessment and REhabilitation in Virtual Reality for Patients With Cancer (CARE-VR4PC)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
1. To assess the cognitive function of patients with cancer by leveraging a validated virtual reality (VR)-based cognitive assessment tool. 2. To evaluate the efficacy of VR-based cognitive rehabilitation therapy (VR-CRT) compared to a control group in improving cognitive functions in cancer patients. Hypothesis Cancer patients with cancer-related cognitive impairment who receive the VR-CRT program will demonstrate significantly greater improvement in cognitive functions, as measured by the validated VR cognition assessment tool, compared to those who receive standard care, both immediately post-intervention and at 3-month follow-up.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Patients With Cancer | Malignant Neoplasm | ALIAS | 0.85 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| VR-based cognitive rehabilitation therapy (VR-CRT) | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- VR-based cognitive rehabilitation therapy (VR-CRT)
- description
- Intervention Arm
- interventionNames
- Behavioral: VR-based cognitive rehabilitation therapy (VR-CRT)
- type
- NO_INTERVENTION
- label
- Standard Care only
- description
- Control arm
Primary outcomes (2)
- measure
- VR Cognition Assessment Tool
- timeFrame
- From enrollment to Day 90 post-intervention (with allowance of + 7 days).
- description
- Effects of VR-based cognitive rehabilitation therapy (VR-CRT) compared to standard care only (Control) on cognitive function measured objectively using VR Cognition Assessment Tool. Mean change in VR Cognition Assessment Tool from Visit 1 (Recruitment) to Visit 2 (Last day of intervention), and Visit 3 (Final follow-up, Day 90 post-intervention with allowance of + 7 days).
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * (1) Cancer (both Solid and haematological) patients with documented cognitive impairments. (2) No history of neurological disorders. (3) Ability to use VR technology. Exclusion Criteria: * Severe visual or auditory impairments, motion sickness, or conditions interfering with VR use.
References
Publications (2)
- RESULTZeng Y, Guan Q, Su Y, Huang Q, Zhao J, Wu M, Guo Q, Lyu Q, Zhuang Y, Cheng AS. A self-administered immersive virtual reality tool for assessing cognitive impairment in patients with cancer. Asia Pac J Oncol Nurs. 2023 Feb 28;10(3):100205. doi: 10.1016/j.apjon.2023.100205. eCollection 2023 Mar. PMID 37012969
- RESULTZeng Y, Zeng L, Cheng ASK, Wei X, Wang B, Jiang J, Zhou J. The use of immersive virtual reality for cancer-related cognitive impairment assessment and rehabilitation: A clinical feasibility study. Asia Pac J Oncol Nurs. 2022 May 17;9(12):100079. doi: 10.1016/j.apjon.2022.100079. eCollection 2022 Dec. PMID 36276883