Clinical trial · Interventional
New Technique of End-to-Side Two-Layered Duct-to-Mucosa Pancreaticojejunostomy With Omental Wrapping and Glue (Glubran 2) During Laparoscopic Whipple Operation
NCT07333755CI-TRIAL-00100661completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Following pancreaticoduodenectomy, omental flaps around the pancreatic anastomosis and adhesive glue can lower the risk of pancreatic fistula, post-pancreatectomy bleeding, and delayed gastric emptying. The overall morbidity following pancreaticoduodenectomy can be decreased with this straightforward and efficient treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Periampullary Carcinoma Resectable | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Pancreaticojejunostomy with omental patch and glue | Procedure | — | UNRESOLVED |
| Pancreaticojejunostomy without omental patch | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- A double-layered, end-to-side pancreaticojejunostomy without omental patch or glue
- interventionNames
- Procedure: Pancreaticojejunostomy without omental patch
- type
- ACTIVE_COMPARATOR
- label
- A double-layered, end-to-side pancreaticojejunostomy with omental patch and Glue
- interventionNames
- Procedure: Pancreaticojejunostomy with omental patch and glue
Primary outcomes (1)
- measure
- The rate of pancreatic fistula after pancreaticoduodenectomy
- timeFrame
- 4 weeks postoperative
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: \- Resectable tumors of the periampullary region Exclusion Criteria: * Pancreatic or duodenal tumors * Irresectability criteria (such as metastases, ascites, or arterial vascular invasion)
References
Publications (1)
- RESULTMaeda A, Ebata T, Kanemoto H, Matsunaga K, Bando E, Yamaguchi S, Uesaka K. Omental flap in pancreaticoduodenectomy for protection of splanchnic vessels. World J Surg. 2005 Sep;29(9):1122-6. doi: 10.1007/s00268-005-7900-3. PMID 16132400