Clinical trial · Interventional
Integrating Smoking Cessation With Low-dose CT-screening for Lung Cancer
Integrating Smoking Cessation With Low-dose CT-screening for Lung Cancer - a Randomized Study
NCT07331519CI-TRIAL-00102697ISC-LDCTrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study investigates effectiveness of different smoking cessation methods and low-dose CT based lung cancer screening
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Smoking Cessation | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| low-dose computed tomography | Other | — | UNRESOLVED |
| Smartphone application | Other | — | UNRESOLVED |
| Written materials for smoking cessation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Arm 1
- description
- Smoking cessation with a smartphone application + LDCT lung cancer screening
- interventionNames
- Other: Smartphone application
- Other: low-dose computed tomography
- type
- ACTIVE_COMPARATOR
- label
- Arm 2
- description
- Smoking cessation with written materials + LDCT lung cancer screening
- interventionNames
- Other: low-dose computed tomography
- Other: Written materials for smoking cessation
- type
- ACTIVE_COMPARATOR
- label
- Arm 3
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 50 Years
- Maximum age
- 74 Years
Show eligibility criteria text
Inclusion Criteria: 1. Able to provide written informed consent 2. Age between 50-74 3. Smoked ≥ 15 cigarettes/day for ≥ 25 years or smoked ≥ 10 cigarettes/day for ≥ 30 years and are active smokers (smoking during the last two weeks) 4. Access to a smartphone (iPhone or Android) Exclusion Criteria: 1. Current or past melanoma, lung, renal or breast cancer 2. A chest CT examination less than one year before inclusion 3. Has known psychiatric or substance abuse disorders that would interfere with cooperation with the requirements of the trial 4. No access to a smartphone (iPhone or Android) 5. Participant is unwilling or unable to comply with treatment and trial instructions 6. Any condition that study investigators consider an impediment to safe trial participation
References
Publications (3)
- RESULTNational Lung Screening Trial Research Team; Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, Gareen IF, Gatsonis C, Marcus PM, Sicks JD. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011 Aug 4;365(5):395-409. doi: 10.1056/NEJMoa1102873. Epub 2011 Jun 29. PMID 21714641
- RESULTde Koning HJ, van der Aalst CM, de Jong PA, Scholten ET, Nackaerts K, Heuvelmans MA, Lammers JJ, Weenink C, Yousaf-Khan U, Horeweg N, van 't Westeinde S, Prokop M, Mali WP, Mohamed Hoesein FAA, van Ooijen PMA, Aerts JGJV, den Bakker MA, Thunnissen E, Verschakelen J, Vliegenthart R, Walter JE, Ten Haaf K, Groen HJM, Oudkerk M. Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial. N Engl J Med. 2020 Feb 6;382(6):503-513. doi: 10.1056/NEJMoa1911793. Epub 2020 Jan 29. PMID 31995683
- RESULTIivanainen S, Kurtti A, Wichmann V, Andersen H, Jekunen A, Kaarteenaho R, Vasankari T, Koivunen JP. Smartphone application versus written material for smoking reduction and cessation in individuals undergoing low-dose computed tomography (LDCT) screening for lung cancer: a phase II open-label randomised controlled trial. Lancet Reg Health Eur. 2024 May 25;42:100946. doi: 10.1016/j.lanepe.2024.100946. eCollection 2024 Jul. PMID 39070744