Clinical trial · Interventional
Exploring Resistance Exercise Training Plus High-Intensity Interval Training (ReHIIT) as Cancer Prehabilitation
Exploring Resistance Exercise Training Plus High-Intensity Interval Training (ReHIIT) as Cancer Prehabilitation: A Healthy Control Group Pilot Study
NCT07313332CI-TRIAL-00122086ReHIIT_CONrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Colorectal cancer is the fourth most common cancer in the UK. Prehabilitation, including exercise, can improve recovery from surgery. This pilot study investigates the combined effects of resistance and high-intensity interval training (ReHIIT) in healthy adults to establish baseline physiology and responses for comparison with cancer patients
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Healthy Adult Male and Female Volunteers | — | UNRESOLVED | — |
| Intervention | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ReHIIT Training Intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Resistance exercise training plus high-intensity interval training (ReHIIT) Intervention
- description
- Participants will complete 8-12 supervised sessions combining high-intensity interval cycling and resistance training at 70% 1-RM.
- interventionNames
- Other: ReHIIT Training Intervention
Primary outcomes (2)
- measure
- Change in anaerobic threshold (CPET-derived)
- timeFrame
- From baseline to 4-weeks after the start of the intervention
- measure
- Change in Muscle mass
- timeFrame
- From baseline to 4-weeks after the start of the intervention
- description
- Derived from DXA and stable isotope assessments of muscle mass (COSIAM, Cegielski et al., 2021)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Participant is willing and able to give informed consent for participation in the study. * Availability and willingness to attend the Royal Derby Hospital site for a minimum of 8 exercise sessions and 2 assessment sessions across the study period. Exclusion Criteria: * BMI \<18 or \>35 kg/m2 * Known active cance * Known metabolic disease * Current known neurological or musculoskeletal conditions (e.g. epilepsy) * Active known cardiovascular, cerebrovascular or respiratory disease - e.g: * Uncontrolled hypertension (systolic BP \> 160 mmHg or diastolic BP \>100 mmhg) * Myocardial infarction within the last 6 months or unstable angina * Heart failure (New York Heart association Class III/IV) * Arrhythmia * Right to left cardiac shunt * Aneurysm of a named blood vessel * COPD * Pulmonary hypertension * Exercise-induced or brittle asthma * Previous stroke/transient ischaemic attack * Abnormal ECG results (at the discrepancy of the study doctor) * Patients who are unable to undergo CPET based on ATS/ACSS guidelines \^ * Pre-existing clotting disorder known to the participant or anticoagulant use * Family history of severe bleeding requiring medical intervention * Participation in a research study in the last 3 months involving invasive procedures or an inconvenience allowance (ALL UoN FMHS UREC approved studies) * Pregnant or breastfeeding
References
Publications (0)
Data not yet available
No reference posted for this study.