Clinical trial · Observational
Effectiveness of Combined Fascial Plane Blocks for Postoperative Pain in Gynecologic Oncology Surgery
Postoperative Analgesic Efficacy of Combined Fascial Plane Blocks After Gynecologic Oncologic Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this prospective observational study is to compare the effectiveness of different postoperative analgesic techniques in patients undergoing major abdominal surgery for gynecologic oncology. The main question is whether the combination of TAP block with Quadratus Lumborum Block (QLB) or Rectus Sheath Block (RSB) provides superior pain relief compared to TAP block alone. All blocks were performed as part of routine clinical anesthesia practice according to the attending anesthesiologist's judgment. No randomization, allocation, or study-directed intervention was performed. Patients were classified into three groups based on the block type they received during standard care: Group 1: TAP Block Only Group 2: TAP + QLB Combination Group 3: TAP + RSB Combination Postoperative data, including pain scores (VAS), opioid consumption, sedation level, heart rate, blood pressure, nausea/vomiting, and length of hospital stay, were collected prospectively. The study aims to determine which block combination provides the best postoperative pain control and recovery profile in patients undergoing gynecologic oncology surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gynecologic Cancers | Malignant Female Reproductive System Neoplasm | ALIAS | 0.90 |
| Postoperative Pain Management | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Group 1:The Transversus Abdominis Plane (TAP) block | Other | — | UNRESOLVED |
| Group 2: TAP Block + Quadratus Lumborum Block (QLB) | Other | — | UNRESOLVED |
| Group 3: TAP Block + Rectus Sheath Block (RSB) | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Group 1: TAP Block Only Group
- description
- Patients who received only Transversus Abdominis Plane (TAP) block as part of routine anesthesia practice. No additional regional block was performed.
- interventionNames
- Other: Group 1:The Transversus Abdominis Plane (TAP) block
- label
- Group 2: TAP + QLB Combination
- description
- Patients who received both TAP block and Quadratus Lumborum Block (QLB) as part of standard clinical anesthesia management.
- interventionNames
- Other: Group 2: TAP Block + Quadratus Lumborum Block (QLB)
- label
- Group 3: TAP + RSB Combination
- description
- Patients who received both TAP block and Rectus Sheath Block (RSB) as part of standard clinical anesthesia management.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria * Age 18 years or older. * ASA physical status I-IV. * Scheduled for major gynecologic oncology surgery (endometrial cancer, ovarian tumor, or cytoreductive surgery). * Undergoing general anesthesia. * Planned postoperative abdominal fascial plane block for pain management (TAP, TAP + QLB, or TAP + RSB). * Able to provide written informed consent. Exclusion Criteria * Refusal to participate or inability to provide informed consent. * Emergency surgery. * Known allergy or contraindication to local anesthetics. * Infection at the block site. * Coagulopathy or anticoagulant use that contraindicates regional anesthesia. * Pre-existing chronic pain conditions or chronic opioid use. * Severe hepatic or renal insufficiency. * Cognitive impairment that prevents reliable pain assessment.
References
Publications (3)
- RESULTYu S, Wen Y, Lin J, Yang J, He Y, Zuo Y. Combined rectus sheath block with transverse abdominis plane block by one puncture for analgesia after laparoscopic upper abdominal surgery: a randomized controlled prospective study. BMC Anesthesiol. 2024 Feb 9;24(1):58. doi: 10.1186/s12871-024-02444-6. PMID 38336613
- RESULTZhu JL, Wang XT, Gong J, Sun HB, Zhao XQ, Gao W. The combination of transversus abdominis plane block and rectus sheath block reduced postoperative pain after splenectomy: a randomized trial. BMC Anesthesiol. 2020 Jan 23;20(1):22. doi: 10.1186/s12871-020-0941-1. PMID 31973700
- RESULTAkerman M, Pejcic N, Velickovic I. A Review of the Quadratus Lumborum Block and ERAS. Front Med (Lausanne). 2018 Feb 26;5:44. doi: 10.3389/fmed.2018.00044. eCollection 2018. PMID 29536008