Effectiveness of Artificial Intelligence-Assisted Colonoscopy for Adenoma Detection in Routine Clinical Practice : a Prospective Multicenter Randomized Trial

Inclusion Criteria:

1. Age 40 to 74 years, inclusive; men and women.
2. Scheduled for elective screening, diagnostic, or surveillance colonoscopy.
3. In generally good condition, mentally competent, and willing to provide written informed consent.

Exclusion Criteria:

1. Known contraindication to colonoscopy or to biopsy.
2. History of colon cancer or previous colonic surgery.
3. Bowel obstruction; confirmed or highly suspected colorectal cancer; inflammatory bowel disease; or active colorectal bleeding.
4. Colorectal polyposis, including a history of familial adenomatous polyposis.
5. Pregnancy or breastfeeding.
6. Participation in another drug or medical device clinical trial within 1 month before enrollment.
7. Any other condition that, in the investigator's judgment, makes the participant unsuitable for this trial.

Withdrawal Criteria:

1. Withdrawal of consent by the participant.
2. Inadequate bowel preparation, defined as a Boston Bowel Preparation Scale (BBPS) total score below 6 or any segment score below 2.
3. Failure to reach the cecum.
4. Newly diagnosed active colitis during the procedure.